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Updated: Apr 15, 2026

Endoscopic Cholesteatoma Surgery
Published on: January 19, 2022
Updates and knowledge gaps in cholesteatoma research.
Chin-Lung Kuo1, An-Suey Shiao2, Matthew Yung3
1Department of Otolaryngology-Head and Neck Surgery, Taipei Veterans General Hospital, No. 201, Section 2, Shipai Road, Beitou District, Taipei City 11217, Taiwan ; Institute of Brain Science, National Yang-Ming University, No. 155, Section 2, Linong Street, Taipei City 11221, Taiwan ; Department of Otolaryngology, National Yang-Ming University School of Medicine, No. 155, Section 2, Linong Street, Taipei City 11221, Taiwan ; Department of Otolaryngology, Taoyuan Armed Forces General Hospital, No. 168, Zhongxing Road, Longtan District, Taoyuan City 32551, Taiwan ; Department of Otolaryngology-Head and Neck Surgery, Tri-Service General Hospital, National Defense Medical Center, No. 325, Section 2, Chenggong Road, Neihu District, Taipei City 114, Taiwan.
Acquired cholesteatoma, a middle ear disease, can cause severe complications without prompt treatment. This review details its history, diagnosis, and management, highlighting the need for advanced medical care.
Area of Science:
- Otolaryngology
- Pathology
Background:
- Acquired cholesteatoma is a destructive, non-cancerous skin growth in the middle ear.
- It can lead to serious intra- and extracranial complications if untreated.
Purpose of the Study:
- To review the history, classification, epidemiology, and pathology of acquired cholesteatoma.
- To detail current diagnostic and management strategies for acquired cholesteatoma.
Main Methods:
- Literature review of historical and recent advancements.
- Analysis of classification, epidemiology, histopathology, and clinical presentation.
- Examination of diagnostic and management approaches.
Main Results:
- Acquired cholesteatoma poses significant risks due to its invasive growth.
- No effective nonsurgical treatments are currently available.
- Understanding the disorder is crucial for developing management strategies.
Conclusions:
- Acquired cholesteatoma requires timely detection and intervention.
- Effective management necessitates a comprehensive understanding of the disease.
- Access to advanced medical care is vital for preventing fatal complications.

