Related Experiment Video
Updated: Apr 15, 2026
Effects of Mechanical Methods Used in Peri-implantitis Treatment on Implant Surface Decontamination and Roughness
Published on: March 14, 2025
Cost-effectiveness of non-surgical peri-implantitis treatments
Stefan Listl1,2, Nadine Frühauf1, Bettina Dannewitz1
1Translational Health Economics Group (THE Group), Department of Conservative Dentistry, Heidelberg University, Heidelberg, Germany.
Aim:
The purpose of the present study was to assess the cost-effectiveness of various alternatives of non-surgical peri-implantitis treatment.
Materials And Methods:
A decision analytical model was constructed and populated with parameter estimates from recent literature for reduction in pocket probing depth (PPD) in response to eight different treatment alternatives. A micro-costing approach combined with an online expert survey was applied to simulate a decision-making scenario taking place in Germany. The treatment alternatives providing the most advantageous cost/outcome combinations were identified according to the net benefit criterion. Uncertainties regarding model input parameters were incorporated via simple and probabilistic sensitivity analysis based on Monte Carlo simulation.
Results:
In the base case scenario, debridement alone, Air-Flow, debridement combined with PerioChip, and debridement combined with local antibiotics were identified as treatment strategies with comparably better value for money than Er:YAG laser monotherapy, Vector System, debridement combined with CHX, and photodynamic therapy. Sensitivity analysis revealed considerable decision uncertainty corresponding to limited evidence about different treatment alternatives for peri-implantitis treatment.
Conclusions:
Derivation of robust treatment recommendations for peri-implantitis requires more comprehensive and patient-centred evidence on peri-implantitis treatments.
