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Experimental intracerebral haematoma in the rat: sequential light microscopical changes
A Jenkins1, W L Maxwell, D I Graham
1Department of Neurosurgery, University of Glasgow.
Neuropathology and Applied Neurobiology
|September 1, 1989
Abstract:
In a small animal model of controlled intracerebral haemorrhage, changes within the haematoma and surrounding tissues were examined by light microscopy in toluidine blue stained semithin sections. Groups of animals were killed at 2, 6, 15, 24 and 48 hours, 2, 4, 8 and 14 days, and 3 months survival. Sequential changes in neurons, glia and leucocytes, together with the gradual absorption of the blood clot and its replacement by an astrocytic scar are described.