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DNA reviews: hair.

E A M Graham1

  • 1Forensic Pathology Unit, University of Leicester, Robert Kilpatrick Building, Leicester Royal Infirmary, Leicester, LE2 7LX, UK, eamg1@le.ac.uk.

Forensic Science, Medicine, and Pathology
|April 15, 2015
PubMed
Summary

Forensic DNA analysis of human and nonhuman hairs presents unique challenges due to the hair

Area of Science:

  • Forensic Science
  • Molecular Biology
  • Genetics

Background:

  • Human and nonhuman hairs are frequently encountered in forensic investigations.
  • Hairs, like other biological samples, can yield crucial identification information through DNA analysis.
  • The biochemical composition of hair poses significant challenges for DNA extraction and analysis.

Purpose of the Study:

  • To review the location and condition of DNA within hair samples.
  • To discuss analytical methods for maximizing DNA information retrieval from hair evidence.

Main Methods:

  • Review of existing literature on hair DNA analysis.
  • Discussion of biochemical challenges in DNA extraction from hair.
  • Overview of techniques to enhance DNA recovery and analysis from hair samples.

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Main Results:

  • DNA is present in hair, but its accessibility and quality vary.
  • Specific analytical methods are required to overcome biochemical hurdles.
  • Successful DNA profiling from hair provides valuable investigative intelligence.

Conclusions:

  • Despite challenges, DNA analysis of hair is a vital forensic tool.
  • Understanding DNA location and condition is key to successful analysis.
  • Optimized analytical methods improve the utility of hair evidence in investigations.