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Solitary pituitary metastasis from HER2-positive breast cancer
Jeremy Kam1, Jeffrey Kam2, G Bruce Mann2
1Department of Neurosurgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia.
Asia-Pacific Journal of Clinical Oncology
|April 15, 2015
Abstract:
The introduction of anti-HER2 therapy with trastuzumab has seen an increase in frequency of central nervous system metastasis as the site of first recurrence. Here, we present a rare case of a 63-year-old woman who presented with an isolated breast carcinoma pituitary metastasis 5 years following treatment for a high-risk breast cancer. This report underscores the changing nature of HER2-positive disease in the post-trastuzumab era.

