[The significance of immunologic factors in the pathogenesis of uveal glaucoma]

A study of the immunologic status in 60 patients with uveal glaucoma, of them 32 patients with chronic uveitis and 28 patients with uveopathies has revealed changes in the immunologic status in these two groups of patients: the reduction of the number of T-lymphocytes and T-suppressors, a tendency to reduction of the number of T-helpers and R-lymphocytes; sensibilization of leucocytes in these two groups of patients to antigens of the choroid, the retina, the iris and to antigens of the trabecular tissue: reduction of indices of migration with these antigens in experiment as compared with control investigations. A conclusion is made that the presence of the signs of immunodeficiency and signs of sensitization to autoantigens make it advisable to use immunocorrective and desensitizing preparations for treatment of patients with uveal glaucoma, especially in pre- and postoperative period.