Operative treatment of combined aortic stenosis and coronary artery disease
Nedzad Kadric1, Emir Kabil1, Emir Mujanovic1
1Center for the Heart BH, Department of Cardiovascular Surgery, Tuzla, Bosnia and Herzegovina.
Insights
Aortic valve replacement combined with coronary artery bypass graft surgery showed higher preoperative symptoms and intra-hospital complications compared to isolated aortic valve replacement. Early diagnosis and risk factor evaluation are crucial for better surgical outcomes.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery
- Thoracic Surgery
Background:
- Aortic valve replacement is standard for severe aortic stenosis.
- Comorbidities, especially coronary heart disease (CHD), complicate the procedure in nearly one-third of patients.
- Patient demographics range from young to elderly with varying comorbidities.
Purpose of the Study:
- To compare outcomes of aortic valve replacement (AVR) with and without concurrent coronary artery bypass grafting (CABG).
Main Methods:
- A retrospective analysis of 120 patients with aortic stenosis from August 2008 to January 2013.
- Patients were divided into isolated AVR (89 patients) and AVR with CABG (31 patients).
- Implanted valves included 89 biological and 31 mechanical.
Main Results:
- Patients undergoing AVR with CABG presented with more severe preoperative symptoms and were younger on average.
- Intra-hospital morbidity and mortality were higher in the combined AVR and CABG group.
- Overall morbidity was 14.3% and mortality was 10.1% across both groups.
Conclusions:
- Preoperative risk assessment and comorbidity evaluation are vital for reducing complications in aortic stenosis patients.
- Early diagnosis of coexisting coronary artery disease and aortic stenosis facilitates timely surgical intervention, preventing myocardial damage.
Introduction:
The aortic valve replacement is a standard operating procedure in patients with severe aortic stenosis. Structure of patients undergoing surgery ranges from young population with isolated mitral valvular disease to the elderly population, which is in addition to the underlying disease additionally burdened with comorbidity. One of the most commonly present factors that further complicate the surgery is coronary heart disease that occurs in, almost, one third of patients with aortic stenosis. The aim is to compare the results of surgery for aortic valve replacement with or without coronary artery bypass graft (CABG).
Patients And Methods:
From August 2008 to January 2013 in our center operated on 120 patients for aortic stenosis. Of this number, 75 were men and 45 women. The average age was 63.37 years (16-78). Isolated aortic valve replacement was performed in 89 patients and in 31 patients underwent aortic valve replacement and coronary bypass surgery. Implanted 89 biological and 31 mechanical valves.
Results:
Patients with associated aortic stenosis and coronary artery disease were more expressed symptomatic symptoms preoperatively to patients with isolated aortic stenosis who were on average younger age. Intra-hospital morbidity and mortality was more pronounced in the group of patients with concomitant aortic valve replacement and coronary bypass surgery. Morbidity was recorded in 17 patients (14.3%) in both groups, while the mortality rate in both groups was 12 patients (10.1%).
Conclusion:
Evaluation of preoperative risk factors and comorbidity in patients with aortic stenosis and coronary artery disease contributes to a significant reduction in intraoperative and postoperative complications. Also, early diagnosis of associated coronary artery disease and aortic stenosis contributes to timely decision for surgery thus avoiding subsequent ischaemic changes and myocardial damage.
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