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Published on: March 8, 2012
Clinical significance of HPV-DNA testing for precancerous cervical lesions
M Moarcăs1, I C Georgescu1, E Brătilă2
1Obstetrics and Gynaecology Department, University Emergency Hospital, Bucharest.
Abstract:
Cervical screening by using cytology was proven efficient in reducing the mortality secondary to cervical cancer, but this method has limitations. High risk HPV infection is essential for cervical cancer development so HPV testing is a new tool used for screening patients for cervical neoplasia. HPV testing was proven most useful for women over 30 years old, in cases in which cytology identified ASC-US and after treatment for CIN. This article outlines the clinical significance of HPV-DNA testing for precancerous cervical lesions and the evidence that stands behind these recommendations.
