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Mining disease genes using integrated protein-protein interaction and gene-gene co-regulation information

Jin Li1, Limei Wang2, Maozu Guo3

  • 1School of Computer Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; School of Life Science and Technology, Harbin Institute of Technology, Harbin, Heilongjiang, China ; College of Bioinformatics Science and Technology, Harbin Medical University, Harbin, Heilongjiang, China.

FEBS Open Bio
|April 15, 2015
PubMed

Keywords:
AD, Alzheimer diseaseCo-regulation networkDisease gene miningGGCRN, gene–gene co-regulation networkHPRD, Human Protein Reference DatabaseKEGG, Kyoto Encyclopedia of Genes and GenomesPPI, protein–protein interactionProtein–protein interactionRWR, random walk with restartRandom walk with restartSNP, single-nucleotide polymorphismeQTLeQTLs, expression quantitative trait loci

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