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Published on: September 30, 2020
Depressive symptoms at discharge from rehabilitation predict future cardiovascular-related hospitalizations
Fiorenza Angela Meyer1, Eva Hugentobler, Stefanie Stauber
1Psychosomatic Medicine Research Group, University of Bern, Bern, Switzerland.
Insights
Depressive symptoms after cardiac rehabilitation predict future cardiovascular hospitalizations. Early intervention for depression in cardiovascular disease (CVD) patients is crucial for improving cardiac prognosis and reducing readmissions.
Area of Science:
- Cardiology
- Psychiatry
- Rehabilitation Medicine
Background:
- Depression is linked to worse outcomes in cardiovascular disease (CVD) patients.
- Assessing depressive symptoms post-cardiac rehabilitation is vital for prognosis.
Purpose of the Study:
- To investigate if depressive symptoms at discharge from cardiac rehabilitation predict future CVD-related hospitalizations.
- To evaluate the association between depression and cardiac prognosis in CVD patients.
Main Methods:
- 486 CVD patients were studied, assessing depressive symptoms using the Hospital Anxiety and Depression Scale (HADS-D) at discharge.
- Follow-up evaluated the predictive value of depressive symptoms for CVD hospitalizations, controlling for covariates.
Main Results:
- Depressive symptoms at discharge (HADS-D≥8) were a significant predictor of CVD-related hospitalizations (HR 1.32, p=0.004).
- Patients with depression at discharge had a 2.5-fold increased risk of poor cardiac prognosis, independent of other factors.
Conclusions:
- Depressive symptoms upon discharge from cardiac rehabilitation are indicative of a poor cardiac prognosis in CVD patients.
- Identifying and managing depression post-rehabilitation is essential for improving patient outcomes.
Objectives:
Depression is associated with poor prognosis in patients with cardiovascular disease (CVD). We hypothesized that depressive symptoms at discharge from a cardiac rehabilitation program are associated with an increased risk of future CVD-related hospitalizations.
Methods:
We examined 486 CVD patients (mean age=59.8±11.2) who enrolled in a comprehensive 3-month rehabilitation program and completed the depression subscale of the Hospital Anxiety and Depression Scale (HADS-D). At follow-up we evaluated the predictive value of depressive symptoms for CVD-related hospitalizations, controlling for sociodemographic factors, cardiovascular risk factors, and disease severity.
Results:
During a mean follow-up of 41.5±15.6 months, 63 patients experienced a CVD-related hospitalization. The percentage of depressive patients (HADS-D≥8) decreased from 16.9% at rehabilitation entry to 10.7% at discharge. Depressive symptoms at discharge from rehabilitation were a significant predictor of outcome (HR 1.32, 95% CI 1.09-1.60; p=0.004). Patients with clinically relevant depressive symptoms at discharge had a 2.5-fold increased relative risk of poor cardiac prognosis compared to patients without clinically relevant depressive symptoms independently of other prognostic variables.
Conclusion:
In patients with CVD, depressive symptoms at discharge from rehabilitation indicated a poor cardiac prognosis.
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