Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Antifungal Agents01:15

Antifungal Agents

89
Amphotericin B is a broad-spectrum antifungal agent that exploits structural differences between fungal and mammalian cell membranes. Its amphipathic structure—featuring a hydrophobic polyene-lactone ring and a hydrophilic region containing mycosamine and carboxylic acid groups—enables selective binding to ergosterol, a sterol predominantly found in fungal plasma membranes. This selective interaction underlies the drug’s antifungal activity, although weak binding to...
89
Bacterial Phylum Cyanobacteria01:30

Bacterial Phylum Cyanobacteria

899
Cyanobacteria are a diverse group of oxygenic, phototrophic bacteria that played a pivotal role in converting Earth’s atmosphere from anoxic to oxygen-rich billions of years ago. They exhibit remarkable morphological diversity, ranging from unicellular forms to filamentous types, with cell sizes varying between 0.5 μm and 100 μm. Cyanobacteria are classified into five groups: Chroococcales (unicellular, dividing by binary fission), Pleurocapsales (unicellular, dividing by...
899
Fungal Group Zygomycota01:29

Fungal Group Zygomycota

2.1K
Zygomycota, previously classified as a distinct fungal group, are primarily terrestrial, saprophytic molds that play a crucial role as decomposers. Recent phylogenetic studies have revealed that these fungi are now divided into two major clades — Mucoromycota, which includes many symbiotic species, and Zoopagomycota, which primarily consists of parasitic and pathogenic fungi. These groups exhibit distinct ecological roles and reproductive strategies while sharing key structural and...
2.1K
Aldehydes and Ketones with HCN: Cyanohydrin Formation Overview01:32

Aldehydes and Ketones with HCN: Cyanohydrin Formation Overview

4.4K
Cyanohydrins are compounds that contain –CN and –OH groups on the same carbon atom. They are formed by the nucleophilic addition of the cyanide ions to the carbonyl group. Cyanide ions are highly basic and nucleophilic and can be generated from HCN under aqueous conditions. However, since HCN is a weak acid, the number of cyanide ions generated is very small. Hence, a small amount of base or KCN/NaCN is added to HCN to increase the concentration of the cyanide ions in the reaction...
4.4K
Fungal Phylum Ascomycota01:28

Fungal Phylum Ascomycota

2.5K
Phylum Ascomycota, a major division within the subkingdom Dikarya, comprises a diverse range of fungal species, including both unicellular yeasts and filamentous molds such as Aspergillus and Penicillium. These fungi thrive in a variety of habitats, from aquatic ecosystems to terrestrial environments, playing crucial ecological and economic roles.Morphology and ReproductionThe defining characteristic of Ascomycetes, commonly referred to as sac fungi, is the ascus—a sac-like structure that...
2.5K
Overview of Fungi01:29

Overview of Fungi

2.6K
Fungi are a diverse group of eukaryotes more closely related to animals than other eukaryotes. Fungal cell walls comprise chitin, a polysaccharide that provides structural strength, and glucans, which contribute to flexibility and integrity. Other polysaccharides, such as mannans and galactosans, may supplement or replace chitin in some fungi. These adaptations, along with their preference for acidic environments and tolerance for high osmotic pressure, enable fungi to thrive in various...
2.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Selective Human Trypsin Inhibitors from Cyanobacteria.

Journal of applied microbiology·2026
Same author

<i>Oxynema</i> <i>mangrovii</i> sp. nov., a new filamentous species (Oscillatoriales, Cyanobacteria) from Atlantic forest mangrove.

Frontiers in microbiology·2026
Same author

Production of nitroaryl secondary metabolites by wood-decaying fungi of <i>Phlebia</i> spp.

Mycologia·2025
Same author

Phosphorylation of peptides by a kinase domain in cyanobactin pathways.

Nature communications·2025
Same author

Elucidation of novel turnagainolides and their biosynthetic gene cluster in <i>Bacillus subtilis</i>.

Applied and environmental microbiology·2025
Same author

Neptunizhulides, Cryptic <i>trans</i>-AT Polyketide Synthase-Derived Metabolites from <i>Paraneptunicella aestuarii</i> NBU2194.

Organic letters·2025

Related Experiment Video

Updated: Apr 15, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
06:47

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Published on: December 5, 2020

7.6K

Antifungal compounds from cyanobacteria.

Tânia K Shishido1, Anu Humisto2, Jouni Jokela3

  • 1Department of Food and Environmental Sciences, Viikki Biocenter 1, University of Helsinki, FI-00014, Helsinki, Finland. tania.shishido@helsinki.fi.

Marine Drugs
|April 15, 2015
PubMed
Summary

This study screened diverse cyanobacteria for antifungal properties, identifying scytophycin and hassallidin production in novel strains. Researchers also found new antifungal compounds in cyanobacteria, highlighting their potential in drug discovery.

More Related Videos

Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks
09:18

Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks

Published on: December 2, 2022

1.5K
Quantifying the Antifungal Activity of Peptides Against Candida albicans
06:45

Quantifying the Antifungal Activity of Peptides Against Candida albicans

Published on: January 13, 2023

3.1K

Related Experiment Videos

Last Updated: Apr 15, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
06:47

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products

Published on: December 5, 2020

7.6K
Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks
09:18

Assessing the Putative Anticryptococcal Properties of Crude and Clarified Extracts from Mollusks

Published on: December 2, 2022

1.5K
Quantifying the Antifungal Activity of Peptides Against Candida albicans
06:45

Quantifying the Antifungal Activity of Peptides Against Candida albicans

Published on: January 13, 2023

3.1K

Area of Science:

  • Microbiology
  • Natural Product Chemistry
  • Pharmacology

Background:

  • Cyanobacteria are prokaryotes known for producing diverse bioactive compounds, including antifungals.
  • Existing knowledge points to peptides, polyketides, and alkaloids as major classes of cyanobacterial antifungals.

Purpose of the Study:

  • To investigate antifungal activities in cyanobacteria from various environmental sources.
  • To identify specific antifungal compounds and the cyanobacterial strains producing them.

Main Methods:

  • Screening of cyanobacterial strains from diverse aquatic environments for antifungal activity.
  • Detection and identification of known antifungal compounds like scytophycin and hassallidin.
  • Characterization of novel antifungal compounds from selected cyanobacterial isolates.

Main Results:

  • Scytophycin, a potent antifungal macrolide, was identified in several Anabaena and Scytonema strains.
  • Antifungal glycolipopeptide hassallidin was detected in Anabaena and Nostoc species.
  • Three cyanobacterial strains produced unidentified antifungal compounds requiring further investigation.

Conclusions:

  • This study expands the known producers of scytophycins to include specific Anabaena strains.
  • The identified antifungal compounds and novel substances underscore the potential of cyanobacteria in drug discovery.
  • All antifungal-producing strains identified belong to the Nostocales or Stigonematales orders.