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Transcytosis of IgG01:15

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Transcytosis is the process in which molecules are internalized by endocytosis, transported across the cell, and released through exocytosis from the opposite end of the cell. Molecules such as insulin, immunoglobulins, and certain nutrients are transferred through the recycling endosomes by recycling and transcytosis.
IgG molecules from a mother undergo transcytosis starting around 13 weeks of gestation. The amount of IgG transferred and entering the fetal blood circulation increases with...
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Characteristic OCT Pattern in Waldenstrom Macroglobulinemia.

Krishnendu Roy1, Sambuddha Ghosh, Bappaditya Kumar

  • 1*MD †MS ‡MBBS Department of Medicine, Medical College Kolkata, Kolkata, India (KR, BK, SB); and Department of Ophthalmology, North Bengal Medical College, Siliguri, India (SG).

Optometry and Vision Science : Official Publication of the American Academy of Optometry
|April 15, 2015
PubMed
Summary
This summary is machine-generated.

Optical coherence tomography (OCT) revealed characteristic patterns aiding the diagnosis of Waldenstrom macroglobulinemia in a patient with vision loss. This imaging technique identified specific retinal changes associated with the condition.

Area of Science:

  • Ophthalmology
  • Hematology
  • Medical Imaging

Background:

  • Waldenstrom macroglobulinemia (WM) is a rare lymphoproliferative disorder.
  • Ocular manifestations of WM can significantly impact vision.

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  • Early diagnosis is crucial for effective management.