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Updated: Apr 15, 2026

High-throughput and Comprehensive Drug Surveillance Using Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry
Published on: April 23, 2019
[The new diagnostic algorithms in early period of acute intoxications with psychotropic preparations]
Abstract:
The patients with acute intoxications with psychotropic preparations were analyzed for physical chemical characteristics of blood albumin at admission to hospital. The common level of reduced thiols in albumin fraction was analyzed too. The more frequent cases of unfavorable course of disease were noted at indicator rate less than 250 mkmol/l than at rates higher than 250 mkmol/l. This occurrence permits to consider this indicator as prognostically significant and to evaluate individual risk of unfavorable course of disease in the given category of patients. Under acute intoxications with psychotropic preparations appllying of fluorescent albumin test permits already at fist day of hospitalization to reveal a subgroup of patients with higher risk of subsequent development of pneumonia.
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