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Treatment of depression and anxiety with internet-based cognitive behavior therapy in patients with a recent

Fredrika Norlund1, Erik M G Olsson2, Gunilla Burell3

  • 1Department of Public Health and Caring Sciences, Uppsala University, Box 564, Uppsala, SE-751 22, Sweden. fredrika.norlund@pubcare.uu.se.

Trials
|April 16, 2015
PubMed

Insights

Internet-based cognitive behavior therapy (iCBT) may reduce depression and anxiety in patients after myocardial infarction (MI). This study evaluated iCBT as a potential accessible treatment option for post-MI patients.

Area of Science:

  • Cardiology
  • Psychiatry
  • Digital Health

Background:

  • Major depression and anxiety are prevalent in patients following myocardial infarction (MI).
  • Depression and anxiety post-MI are linked to adverse cardiovascular outcomes and event recurrence.
  • Cognitive behavior therapy (CBT) is effective for depression and anxiety but its internet-based form (iCBT) has not been studied in post-MI patients.

Purpose of the Study:

  • To evaluate the efficacy of an internet-based cognitive behavior therapy (iCBT) intervention.
  • To assess the impact of iCBT on depression and anxiety symptoms in patients with a recent myocardial infarction (MI).
  • To determine if iCBT can be an accessible treatment option for the post-MI population.

Main Methods:

  • A randomized, controlled, prospective, multicenter study design.
  • 500 participants randomized two months post-MI to either iCBT or a control group.
  • The iCBT intervention involved a 14-week self-help program with online psychological support; primary outcome was change in self-rated anxiety and depression symptoms.

Main Results:

  • The study is designed to evaluate the intervention's effectiveness.
  • An internal pilot indicated sufficient study acceptability and treatment engagement.
  • Results regarding the primary outcome (reduction in anxiety and depression symptoms) are pending.

Conclusions:

  • The study evaluates a novel iCBT intervention for depression and anxiety in post-MI patients.
  • If effective, iCBT offers advantages as an accessible treatment.
  • iCBT could be integrated into the standard care for patients recovering from MI.
Abstract

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