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Childhood cancer survivors treated with radiation face increased skin cancer risk. This study tests interventions to boost skin self-exams and physician screenings, aiming for earlier detection and improved outcomes in this high-risk group.

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Area of Science:

  • Oncology
  • Dermatology
  • Public Health

Background:

  • Childhood cancer survivors treated with radiation have a significantly higher risk of developing secondary skin cancers.
  • Early detection of skin cancer in this population is crucial for improved outcomes, as recommended by the National Cancer Institute and Children's Oncology Group.
  • This study aims to enhance skin self-examination and clinical skin examination rates among adult survivors of childhood cancer who received radiation therapy.

Purpose of the Study:

  • To increase the rates of skin self-examinations and clinical skin examinations in adult survivors of childhood cancer treated with radiation.
  • To evaluate the effectiveness of different intervention components in promoting skin cancer screening vigilance.
  • To address barriers to screening by providing education and leveraging mobile health technology.

Main Methods:

  • A randomized controlled trial with a 3-group comparative effectiveness design.
  • Group 1: Patient Activation and Education (PAE) via text, print, and web.
  • Group 2: PAE plus physician activation (PAE+MD) with educational materials and full-body skin exams.
  • Group 3: PAE+MD plus teledermoscopy (PAE+MD+TD) with a dermatoscope for lesion photography.

Main Results:

  • The study is designed to compare the effectiveness of three different intervention strategies.
  • It aims to identify the most effective intervention for improving skin examination vigilance in this high-risk population.
  • Results will indicate which combination of patient and physician activation, with or without teledermoscopy, best enhances screening behaviors.

Conclusions:

  • The study addresses barriers to skin cancer screening in childhood cancer survivors through education and motivation.
  • Innovative mobile health technology is employed to encourage self-examinations and physician consultations.
  • The comparative effectiveness design will determine the optimal intervention for enhancing vigilance and promoting timely treatment of worrisome skin lesions.