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Should we search Chinese biomedical databases when performing systematic reviews?

Jérémie F Cohen1,2,3, Daniël A Korevaar4, Junfeng Wang5

  • 1Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center - University of Amsterdam, Room J1B-210, PO Box 22700, 1100 DE, Amsterdam, The Netherlands. j.f.cohen@amc.uva.nl.

Systematic Reviews
|April 16, 2015
PubMed
Summary

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Systematic reviews rarely search Chinese biomedical databases, missing significant clinical evidence. Incorporating these resources could improve evidence synthesis for rheumatoid arthritis and other conditions.

Area of Science:

  • Biomedical Informatics
  • Evidence-Based Medicine
  • Systematic Review Methodology

Background:

  • Chinese biomedical databases hold substantial research relevant to systematic reviews.
  • The extent of their utilization in evidence synthesis remains largely unknown.

Purpose of the Study:

  • To investigate the impact of including Chinese databases in systematic reviews.
  • To assess the frequency of Chinese database usage by Cochrane reviewers.

Main Methods:

  • Comparison of two systematic reviews on anti-cyclic citrullinated peptide accuracy for rheumatoid arthritis, one including Chinese databases, the other excluding them.
  • Systematic overview of Cochrane reviews (inception to 2014) to determine Chinese database search prevalence.

Main Results:

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  • Reviews including Chinese databases identified significantly more studies.
  • Only a small fraction (less than 3%) of Cochrane reviews searched Chinese databases.
  • Chinese databases index numerous journals not covered by MEDLINE.

Conclusions:

  • Excluding Chinese databases may lead to the omission of substantial clinical evidence.
  • Cochrane reviewers have underutilized Chinese databases in their systematic reviews.
  • Future efforts should focus on systematically evaluating and integrating Chinese resources into systematic reviews.