Related Experiment Video
Updated: Apr 14, 2026

Whole-body PET/MRI of Pediatric Patients: The Details That Matter
Published on: December 19, 2017
[Whole-body-CT in Severely Injured Children. Results of Retrospective, Multicenter Study with Patients from the
P Hilbert-Carius1, G O Hofmann2, R Lefering3
1Klinik für Anästhesiologie, Intensiv- u. Notfallmedizin, BG-Kliniken Bergmannstrost, Halle (Saale).
Insights
Whole-body CT scans do not improve survival rates in pediatric trauma patients. A non-whole-body CT approach offers equivalent outcomes with reduced radiation exposure for children.
Area of Science:
- Trauma Care
- Diagnostic Imaging
- Pediatric Emergency Medicine
Background:
- Whole-body CT (WBCT) is standard for adult trauma patients, reducing mortality.
- The benefit of WBCT in pediatric trauma is debated due to radiation concerns.
- Evidence is needed to determine if WBCT improves survival in children.
Purpose of the Study:
- To evaluate the effectiveness of WBCT versus non-WBCT in pediatric trauma patients.
- To compare survival rates and mortality ratios between WBCT and non-WBCT groups in children.
- To assess the utility of WBCT in pediatric trauma care.
Main Methods:
- Retrospective, multicenter study using TraumaRegister DGU(®) data.
- Included children (1-15 years) and adults (16-50 years) with Injury Severity Score (ISS) > 9.
- Calculated Revised Injury Severity Classification (RISC) and Standardized Mortality Ratio (SMR); compared WBCT vs. non-WBCT groups.
Main Results:
- 1,456 pediatric and 20,796 adult trauma patients were analyzed.
- Adults receiving WBCT had a significantly lower SMR (improved survival).
- Pediatric trauma patients showed no survival advantage with WBCT compared to non-WBCT.
Conclusions:
- WBCT does not offer a survival benefit for pediatric trauma patients.
- Non-WBCT is a viable alternative for children, providing equivalent outcomes.
- Non-WBCT reduces radiation exposure in pediatric trauma cases.
Background:
A fast and comprehensive diagnostic by means of whole-body CT has been shown to reduce mortality in the adult trauma population. Therefore whole-body CT seems to be the standard in adult trauma-patients. Due to the higher radiation exposure of whole-body CT the use of this diagnostic toll in pediatric trauma patients is still under debate. It is not yet clear if whole-body CT in children can increase the probability of survival.
Method:
In a retrospective, multicenter study, we used the data recorded in the TraumaRegister DGU(®) to calculate the probability of survival according to the revised injury severity classification (RISC) and standardized mortality ratio (SMR). The SMR reflects the ratio of recorded to expected mortality. Included in the study were all children (1-15 years) and adults (16-50 years) with an Injury Severity Score (ISS)>9, who were directly admitted to the hospital from the scene of accident. We compared the groups of patients given whole-body CT or non-whole-body CT. Subgroup analysis was performed for children 1-9 years, children 10-15 years and adults.
Results:
A total of 1,456 pediatric trauma patients (mean age 9.9 years) and 20,796 adults (mean age 32.7 years) were included in the study. In contrast to adult trauma patients, were the SMR in the whole-body CT group was significant lower; we observed no advantage for the whole-body CT in pediatric trauma patients.
Conclusion:
Due to the missing advantage of whole-body CT in the pediatric trauma population and the higher radiation exposure of whole-body CT a non-whole-body CT approach seems equivalent with a lower radiation exposure.
Related Concept Videos
Imaging Studies III: Computed Tomography
Computed Tomography
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
Imaging Studies for Cardiovascular System V: CT
![Semi-quantitative Assessment Using [18F]FDG Tracer in Patients with Severe Brain Injury](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F58641.jpg&w=3840&q=50)
