Related Experiment Video
Updated: Apr 14, 2026

A Retrograde Implantation Approach for Peritoneal Dialysis Catheter Placement in Mice
Published on: July 20, 2022
Successful treatment of Cryptococcus laurentii peritonitis in a patient on peritoneal dialysis
Marina Asano1, Makoto Mizutani, Yasuko Nagahara
1Department of Nephrology, Handa Municipal Hospital, Japan.
Abstract:
A 32-year-old man on peritoneal dialysis (PD) was hospitalized for seven days due to fever. A diagnosis of yeast-like fungal peritonitis was made by Gram staining. The patient was started on intravenous micafungin and oral fluconazole therapy following removal of the PD catheter. A fungal pathogen was isolated from the peritoneal fluid and identified as Cryptococcus species. Based on antifungal susceptibility testing, the treatment was changed to voriconazole and continued for 3 months. A genetic analysis identified the isolate as Cryptococcus laurentii (C. laurentii). This patient was diagnosed with C. laurentii PD-related peritonitis and was successfully treated with voriconazole and removal of the PD catheter.
Insights
A rare case of fungal peritonitis caused by Cryptococcus laurentii in a patient undergoing peritoneal dialysis was successfully treated. The treatment involved removing the dialysis catheter and a 3-month course of voriconazole.
Area of Science:
- Infectious Diseases
- Nephrology
- Mycology
Background:
- Peritonitis is a serious complication in patients undergoing peritoneal dialysis (PD).
- Fungal peritonitis, though less common than bacterial peritonitis, poses significant challenges in management.
- Cryptococcus species are opportunistic fungi that can cause severe infections.
Related Concept Videos
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Peritoneal Dialysis III: Nursing Management
Extracorporeal Removal of Drugs: Peritoneal Dialysis and Hemodialysis
Peritoneal Dialysis I: Introduction and Procedure
Kidney Transplant II: Surgical Procedure
Extracorporeal Removal of Drugs: Continuous Renal Replacement Therapy

