Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

550
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
550
Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

521
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
521
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

665
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
665
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.5K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.5K
Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

370
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
370
Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

785
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
785

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same authorSame journal

External validation of the P-Score in the prospective, pre-biopsy DEPROMP cohort: integrated mpMRI and PSMA PET/CT risk stratification for prostate cancer detection.

European journal of nuclear medicine and molecular imaging·2026
Same author

Habenula volume alterations in adults born very preterm.

Scientific reports·2026
Same author

Stereotactic Microwave Ablation of Early-Stage Hepatocellular Carcinoma in Patients with Transjugular Intrahepatic Portosystemic Shunts: A Matched Case-Control Study.

Cardiovascular and interventional radiology·2026
Same author

Molecular imaging and immune cell adhesion via vascular adhesion protein-1 in idiopathic inflammatory myopathy: a case report.

EULAR rheumatology open·2026
Same author

[<sup>68</sup>Ga]Ga-DOTA-Siglec-9 PET/CT in newly diagnosed giant cell arteritis: an inflammation-specific, treatment-responsive molecular imaging biomarker.

RMD open·2026
Same author

NOX4 signatures in human abdominal aortic aneurysm reveal links to vascular cell plasticity, extracellular matrix remodeling and inflammation.

Free radical biology & medicine·2026

Related Experiment Video

Updated: Apr 14, 2026

MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

12.5K

Imaging large vessel vasculitis with fully integrated PET/MRI: a pilot study.

Ingo Einspieler1, Klaus Thürmel, Thomas Pyka

  • 1Department of Nuclear Medicine, Technische Universität München, Klinikum rechts der Isar, Ismaningerstr. 22, 81675, Munich, Germany, ingo.einspieler@tum.de.

European Journal of Nuclear Medicine and Molecular Imaging
|April 17, 2015
PubMed
Summary

Hybrid positron emission tomography (PET)/MRI is feasible for evaluating large vessel vasculitis (LVV), showing comparable results to PET/CT for disease extent and activity assessment.

More Related Videos

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.6K
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.7K

Related Experiment Videos

Last Updated: Apr 14, 2026

MRI and PET in Mouse Models of Myocardial Infarction
10:46

MRI and PET in Mouse Models of Myocardial Infarction

Published on: December 19, 2013

12.5K
Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis
08:40

Positron Emission Tomography Imaging for In Vivo Measuring of Myelin Content in the Lysolecithin Rat Model of Multiple Sclerosis

Published on: February 28, 2021

4.6K
Whole-body PET/MRI of Pediatric Patients: The Details That Matter
10:02

Whole-body PET/MRI of Pediatric Patients: The Details That Matter

Published on: December 19, 2017

15.7K

Area of Science:

  • Medical Imaging
  • Nuclear Medicine
  • Radiology

Background:

  • Large vessel vasculitis (LVV) diagnosis and monitoring require accurate imaging techniques.
  • Hybrid imaging modalities offer potential for improved diagnostic capabilities.

Purpose of the Study:

  • To assess the feasibility of hybrid [(18)F]fluorodeoxyglucose (FDG) PET/MRI in patients with LVV.
  • To compare PET/MRI with PET/CT regarding visual and quantitative parameters for LVV assessment.
  • To evaluate the utility of PET/MRI in determining LVV disease activity and extent.

Main Methods:

  • 16 [(18)F]FDG PET/MRI and 12 [(18)F]-FDG PET/CT scans were performed in 12 LVV patients.
  • Vessel wall MRI (T1/T2-weighted, CE-MRA) was used for anatomical correlation.
  • Visual scores, SUVmax, and TBR were compared between PET/MRI and PET/CT.
  • Correlations between C-reactive protein (CRP), quantitative PET results, and disease extent were analyzed.

Main Results:

  • PET/MRI and PET/CT demonstrated strong correlations in TBR, SUVmax, and visual scores (r >= 0.84).
  • No significant differences were found in SUVmax or visual scores between the two modalities.
  • PET/MRI identified 95 vasculitis regions when combined with MRI, compared to 49 with MRI/CE-MRA alone.
  • Strong correlations were observed between CRP and disease extent in PET/MRI (r=0.92, p<0.0001).

Conclusions:

  • Hybrid PET/MRI is a feasible imaging modality for patients with LVV.
  • PET/MRI demonstrates high potential for accurately assessing both the extent and activity of LVV.