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Updated: Apr 14, 2026
09:36
Effect of Hyaluronic Acid 35 kDa on an In Vitro Model of Preterm Small Intestinal Injury and Healing Using Enteroid-Derived Monolayers
Published on: July 28, 2022
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Hyaluronic acid and wound healing
Manuela G Neuman1, Radu M Nanau, Loida Oruña-Sanchez
1In Vitro Drug Safety and Biotechnology and Department of Pharmacology and Toxicology, University of Toronto.
Summary
Hyaluronic acid demonstrates safety and efficacy in skin repair, showing promise for wound healing applications. This study clarifies its uses in tissue regeneration and dermatological treatments.
Area of Science:
- Dermatology
- Biomedical Engineering
- Regenerative Medicine
Background:
- Developed an experimental model for ethanol-induced skin and liver toxicity using human cells.
- Previous research established the foundation for this study on cellular toxicity models.
Purpose of the Study:
- To evaluate if hyaluronic acid can reduce skin necrosis.
- To further elucidate the applications of hyaluronic acid in wound repair across various study types.
Main Methods:
- Conducted a systematic literature review focusing on "hyaluronic acid" and "wound healing".
- Searched PubMed for relevant studies published between 2010 and 2014.
Main Results:
- Hyaluronic acid is utilized in tissue regeneration, both independently and with other medicines.
- Hyaluronic acid scaffolds have been employed to incorporate basic fibroblast growth factor for regenerative purposes.
Conclusions:
- Hyaluronic acid extracts are confirmed as safe and effective for skin repair applications.
- The findings support the use of hyaluronic acid in promoting wound healing and tissue regeneration.
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