Cold snare polypectomy for large sessile colonic polyps: a single-center experience

Area of Science:

• Gastroenterology
• Endoscopic procedures
• Colorectal cancer prevention

Background:

• Colonoscopic polypectomy significantly reduces colorectal cancer risk and mortality.
• Cold snare polypectomy (CSP) is associated with lower post-polypectomy bleeding rates compared to conventional methods.
• CSP has traditionally been limited to smaller polyps (<1 cm).

Purpose of the Study:

• To evaluate the feasibility and outcomes of CSP for large sessile colorectal polyps (≥10 mm).
• To assess the safety and efficacy of CSP in a challenging polyp size category.

Main Methods:

• Retrospective analysis of CSP outcomes in patients with sessile polyps ≥10 mm.
• Evaluation of adverse events and residual polyp rates on follow-up colonoscopy.

Main Results:

• CSP was feasible for large sessile polyps (≥10 mm) without reported adverse events.
• An acceptable rate of residual polyp was observed on follow-up colonoscopy.
• CSP demonstrated potential for managing larger polyps effectively.

Conclusions:

• Cold snare polypectomy is a feasible and safe option for large sessile colorectal polyps.
• Further prospective studies are warranted to compare CSP with cautery-based methods for large polyps regarding efficacy and complication rates.