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Simple and Effective Approach for Treating Non-healing Ulcers After a Snakebite
Basavraj Nagoba1, Arun Rao2, Bharat Wadher2
1MIMSR Medical College, Latur, India;
Citric acid effectively treats snakebite ulcers resistant to antibiotics. Topical citric acid ointment healed 96% of ulcers, offering a promising alternative treatment.
Area of Science:
- Wound healing
- Antimicrobial therapy
- Dermatology
Background:
- Snakebite ulcers present a significant challenge, often resisting conventional antibiotic treatments.
- Identifying novel antimicrobial agents is crucial for managing complex wound infections.
Purpose of the Study:
- To evaluate citric acid as a sole antimicrobial agent for treating snakebite ulcers.
- To assess the efficacy of topical citric acid in non-healing snakebite ulcers.
Main Methods:
- Culture and susceptibility testing of swabs from 52 snakebite ulcers.
- Determination of Minimum Inhibitory Concentration (MIC) for citric acid.
- Topical application of citric acid ointment.
Main Results:
- Staphylococcus aureus and Pseudomonas aeruginosa were the predominant bacterial isolates.
- Citric acid demonstrated antimicrobial activity with MICs ranging from 500-2500 µg/mL.
- Topical citric acid ointment achieved complete healing in 96.15% of cases.
Conclusions:
- Citric acid is a safe and effective alternative for managing snakebite ulcers.
- This approach shows high healing rates in antibiotic-resistant cases.
- Further research into citric acid's role in wound care is warranted.
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