Related Experiment Video
Updated: Apr 14, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
Published on: March 28, 2025
Hybrid vascular surgery approaches for multilevel arterial occlusive disease
Kerem Oral1, Mehmet Ezelsoy1, Kemal Ayalp2
1Department of Cardiovascular Surgery, Istanbul Florence Nightingale Hospital, Istanbul, Turkey.
Insights
Hybrid vascular approaches offer a less invasive and effective treatment for multilevel peripheral arterial occlusive disease, improving limb survival rates in older patients with complex comorbidities.
Area of Science:
- Vascular Surgery
- Peripheral Arterial Disease
- Hybrid Interventions
Background:
- Multilevel arterial occlusive disease (MAOD) presents significant challenges in vascular surgery, particularly in elderly patients with comorbidities.
- Inflow and outflow constrictions in MAOD can compromise the success and longevity of traditional bypass procedures.
- High-risk patients often have complex vascular disease necessitating innovative treatment strategies.
Purpose of the Study:
- To evaluate the efficacy and outcomes of hybrid vascular approaches for treating patients with multilevel peripheral arterial occlusive disease.
- To assess the safety and feasibility of hybrid techniques in a challenging patient population.
Main Methods:
- A retrospective study of 38 patients with MAOD treated with hybrid vascular approaches between 2005 and 2011.
- Patients presented with symptoms including claudication, rest pain, and tissue integrity issues.
- Data collected included patient demographics, clinical presentation, procedural details, and outcomes.
Main Results:
- The study included 38 patients (mean age 68.1 years, 89% male) with MAOD.
- The hybrid approach resulted in a high extremity survival rate of 94.1% at the end of follow-up.
- Complications included one case requiring secondary intervention and amputation, and minor toe amputations in 14% of patients.
Conclusions:
- Hybrid vascular approaches represent a viable, less invasive treatment option for multilevel peripheral arterial occlusive disease.
- This approach demonstrates sufficiency in managing complex vascular disease, leading to favorable limb salvage outcomes.
- The findings support the consideration of hybrid techniques for high-risk patients with MAOD.
Background:
The incidence of multilevel vascular occlusive disease is increased with patient age. Multilevel arterial occlusive disease cases are some of the hardest in the vascular surgical realm because of the comorbidities. In these high-risk patients inflow constrictions may limit the success of distal bypasses. At the same time the constrictions in the outflow may necessitate long bypass circuits that have less long-term patency rates.
Methods:
Our study included 38 patients with multilevel arterial occlusive disease to whom hybrid vascular approaches were applied between January 2005 and December 2011 in Şişli Florence Nightingale Hospital. The patient group had a mean age of 68.1 (48-98) and included 29 male (89%) and 9 female (11%) patients. Complaints were claudication under 100 meters of walking in 19 patients (50%), resting pain in 14 patients (36%), and disturbed tissue integrity in 5 patients (14%). Mean in-hospital stay was calculated to be 6.4 days (4-15). In one patient (2.6%), a second procedure was necessary due to graft thrombosis and this case resulted in amputation under the level of the knee. Minor toe amputations in a second session were applied to 5 patients (14%) with symptoms of foot sores. Wound infections occurred in two patients (5%) and were treated with antibiotherapy and wound care.
Results:
At the end of the follow-up time, extremity survival was found to be 94.1%.
Conclusions:
In the treatment of multilevel peripheral arterial occlusive disease, a hybrid approach is a treatment option which is less invasive and sufficient.
More Related Videos
13:48Reduction of Radiation Exposure during Endovascular Treatment of Peripheral Arterial Disease Combining Fiber Optic RealShape Technology and Intravascular Ultrasound
Published on: April 21, 2023
14:58Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
Published on: October 20, 2017
Related Concept Videos
Aneurysm III: Interprofessional Care
Peripheral Artery Disease III: Interprofessional Care
Peripheral Artery Disease V: Postoperative Nursing Management