Related Experiment Video
Updated: Apr 14, 2026

Experimental Human Pneumococcal Carriage
Published on: February 15, 2013
[Prophylactic use of anti-influenza and anti-pneumococcal vaccines in industrial workers]
Abstract:
Efficiency of vaccination against respiratory tract infections was proved by long worldwide experience. The article covers analysis of vaccination results in 26,852 workers of major industrial enterprises of RUSAL company in 12 cities of Russia, using anti-influenza vaccine Vaxigrip, and combined vaccination in 466 workers with anti-influenza vaccine Vaxigrip and anti-pneumococcal vaccine Pneumo 23. Reference group of non-vaccinated workers randomly included 7,520 workers of the same enterprises and comparable in age and length of service. Efficiency of vaccination was assessed in a year through analysis of transitory disablement morbidity due to respiratory tract infections and clinical data. Vaccinated with Vaxigrip and Pneumo 23, the workers with chronic bronchitis demonstrated inconstant cough in statistically significantly more rare occasions in comparison with non-vaccinated workers (24,75% vs. 75,25% in vaccinated and non-vaccinated groups respectively, p < 0,05). In the group vaccinated with Vaxigrip, the transitory disablement morbidity equalled 42,06 per 1000 workers. In the group vaccinated with Vaxigrip and Pneumo 23, the transitory disablement morbidity equalled 46,07 per 1000 workers. In the group of non-vaccinated workers, the morbidity equalled 158,6 per 1,000 workers.
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