Related Experiment Video
Updated: Apr 14, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
Lyme disease presenting as multiple ischaemic strokes
Sui Li1, Michal Vytopil1, Kinan Hreib1
1Department of Neurology, Lahey Hospital & Medical Center, Burlington, Massachusetts, USA.
Abstract:
A 46-year-old man presented with recurrent left hemiparesis and headache. MRI of brain showed an acute right pontine and subacute right thalamic infarcts and MR angiogram showed multiple intracranial arterial stenoses, suggesting cerebral vasculopathy. There was a cerebrospinal fluid lymphocytic pleocytosis with Borrelia burgdorferi antibodies. Central nervous system Lyme disease occasionally presents with ischaemic strokes; this case is unusual in showing vasculopathy on brain imaging, supporting meningovasculitis as the likely mechanism.
Insights
Central nervous system Lyme disease can cause strokes. This case highlights unusual brain imaging findings of vasculopathy in a patient with Lyme disease, suggesting meningovasculitis as the cause of cerebral infarcts.
Area of Science:
- Neurology
- Infectious Diseases
- Neuroimaging
Background:
- Cerebrovascular events, such as ischemic strokes, are rare but recognized complications of Central Nervous System (CNS) Lyme disease.
- Typical presentations of CNS Lyme disease include meningitis, radiculoneuritis, and encephalitis, with stroke being an atypical manifestation.
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