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Updated: Apr 14, 2026

A Middle Cerebral Artery Occlusion Technique for Inducing Post-stroke Depression in Rats
Published on: May 22, 2019
Changes in life habits affected by mild stroke and their association with depressive symptoms
1School of Rehabilitation AND. Centre for Interdisciplinary Research in Rehabilitation of Greater Montreal (CRIR) , University of Montreal, , Canada.
Objectives:
To examine changes in sleep, driving, employment, relationships and leisure in the first year after a mild stroke and explore the association between the presence of depressive symptoms and improvement in participation 6 months later.
Methods:
Social participation (LIFE-H 3.1) and depressive symptoms (Beck Depression Inventory-II) were measured in the first month (T0), 6 months and 1 year after mild stroke. Descriptive statistics and logistic regression analysis were used.
Results:
There were 186 participants at T0, 149 at 6 months and 138 at 1 year. Mean age at T0 was 63.3 ± 12.5 years and 81/186 (43.6%) were female. All the life habits examined showed an improvement at 6 months and 1 year, except for having a sexual relationship (p = 0.12) at 6 months, and sleep at 6 months (p = 0.15) and 1 year (p = 0.07). A significant association between the presence of depressive symptoms at T0 and reduced participation at 6 months was obtained for driving a vehicle (p = 0.02), participating in sports or recreational activities (p = 0.01) and interpersonal relationships (p = 0.003), but not for holding a paid job (p = 0.06).
Conclusion:
Systematic screening for depression should be carried out upon discharge from hospital in order to better target individuals who have had a mild stroke and are in further need of rehabilitation.
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