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Mucosal pigmentation of the hard palate in a patient taking imatinib

Alexandra Lyne1, Alex Creedon1, Basil Malcolm West Bailey1

  • 1Department of Oral and Maxillofacial Surgery, Ashford and St Peter's Hospitals, Surrey, UK.

BMJ Case Reports
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Pigmentation

The color of the skin is influenced by a number of pigments, including melanin, carotene, and hemoglobin. Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. The melanin is transferred to the keratinocytes via melanosomes.
Melanin occurs in two primary forms: eumelanin that provides black and brown pigment and pheomelanin that provides red color. Dark-skinned individuals produce more melanin than those with pale...
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