Related Experiment Video
Updated: Apr 14, 2026
07:05
Operant Protocols for Assessing the Cost-benefit Analysis During Reinforced Decision Making by Rodents
Published on: September 10, 2018
6.6K
Thresholds for the cost-effectiveness of interventions: alternative approaches
Elliot Marseille1, Bruce Larson2, Dhruv S Kazi3
1Health Strategies International, 555 Fifty-ninth Street, Oakland, California, 94609, United States of America (USA).
Bulletin of the World Health Organization
|April 18, 2015
Summary
The World Health Organization
Area of Science:
- Health economics
- Public health policy
- Intervention evaluation
Background:
- Many countries utilize World Health Organization's Choosing Interventions that are Cost-Effective (WHO-CHOICE) cost-effectiveness thresholds.
- These thresholds define cost-effectiveness based on a country's gross domestic product (GDP) per capita.
Purpose of the Study:
- To critically evaluate the utility of WHO-CHOICE cost-effectiveness thresholds in public health decision-making.
- To highlight the limitations of these thresholds in resource allocation and trade-off assessments.
- To propose alternative approaches for applying cost-effectiveness criteria.
Main Methods:
- Analysis of the theoretical underpinnings and practical application of WHO-CHOICE thresholds.
- Critique of the thresholds' impact on decision-making and resource allocation.
- Exploration of alternative frameworks for cost-effectiveness analysis in public health.
Main Results:
- Reliance on WHO-CHOICE thresholds diminishes the value of cost-effectiveness analyses.
- The thresholds lack theoretical justification and practical utility for ranking interventions.
- Current thresholds are too low, failing to exclude ineffective interventions and hindering trade-off assessments.
Conclusions:
- WHO-CHOICE thresholds offer limited value for public health decision-making.
- Alternative methods are needed for robust cost-effectiveness analysis and resource allocation.
- A more nuanced approach is required to assess the true value and affordability of health interventions.
Related Concept Videos
01:29Nursing Interventions II: Selecting and Classifying the Nursing Interventions
3.7K
Creating and executing a nursing diagnosis helps nurses plan care and guide patient, family, and community interventions. They are developed based on a patient's physical evaluation and support measuring the outcomes. It is not recommended to select random interventions throughout the planning process. Instead, consider the following six essential factors when choosing interventions:
3.7K
01:23Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
575
Biopharmaceutical studies constitute a vital field aiming to enhance drug delivery methods and refine therapeutic approaches, drawing upon diverse interdisciplinary knowledge. In research methodologies, the choice between controlled and non-controlled studies significantly influences the study's reliability and accuracy.
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast,...
575
01:13Therapeutic Index
7.8K
The therapeutic index of a drug is a key parameter in pharmacology that quantifies the relative safety of a drug by calculating the ratio between the dose that causes toxicity in half the population (50%) to the dose that proves to be effective for half the population (50%). It provides a spectrum of doses for a particular drug ranging from effective to potentially toxic. To illustrate, consider an anticoagulant agent like warfarin. It possesses a narrow window within its therapeutic index to...
7.8K
01:12Hazard Ratio
737
The hazard ratio (HR) is a widely used measure in clinical trials to compare the risk of events, such as death or disease recurrence, between two groups over time. It reflects the ratio of hazard rates—the instantaneous risk of the event occurring—between a treatment group and a control group. This measure provides valuable insights into the relative effectiveness of a treatment by assessing how the risk of an event differs between the two groups.
For example, in a clinical trial...
For example, in a clinical trial...
737
01:22Healthcare Associated Infections II: Preventive Measures
5.0K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
5.0K
01:26Methods Of Healthcare Delivery System
4.3K
At the different levels of the healthcare system, we see varying methods of healthcare used. These methods include managed care systems, case management, and primary healthcare.
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
Managed Care System:
The managed care system is designed to control the cost while maintaining the quality of care. The patient's care from admission to discharge is planned by the primary care provider or the case manager, also known as the gatekeeper. In a managed care system, the number of care providers is...
4.3K