Is glial heme oxygenase-1 suppression in neurodegenerative disorders permissive for neural repair?
1Bloomfield Centre for Research in Aging, Lady Davis Institute for Medical Research, Jewish General Hospital, Department of Neurology & Neurosurgery and Department of Medicine, McGill University, Montreal, Quebec, Canada.
Neural Regeneration Research
|April 18, 2015
Abstract
No abstract available in PubMed .
Related Concept Videos
Neurogenesis and Regeneration of Nervous Tissue
2.1K
In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...
2.1K
Glial Cells
96.9K
Overview
96.9K


