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Updated: Apr 14, 2026

Enteric Bacterial Invasion Of Intestinal Epithelial Cells In Vitro Is Dramatically Enhanced Using a Vertical Diffusion Chamber Model
Published on: October 22, 2013
[The biological characteristics of dominated agents of acute enteric infections]
Abstract:
In 2003-2012 the rate of increase of morbidity of acute enteric infections caused by opportunistic microorganisms came to 3.6%. In the etiologic structure prevailed Klebsiella pneumoniae, Staphylococcus aureus and Enterobacter cloacae. Their percentage varied from 70.5% to 81.6%. The opportunistic microorganisms isolated from feces of patients with acute enteric infections and individuals from control group characterized by presence of pathogenic factors of broad spectrum. The adhesive characteristics were manifested by 50.8±4.4% of analyzed cultures isolated from patients with symptoms of diarrhea infection and by 19.5±3.5% in control group. The anti-lysozyme activity was manifested correspondingly in 86.2±3.0% and 61.7±4.3% of strains. The anti-complement activity was manifested in 70.8±3.9% and 61.7±4.3% of strains. The anti-interferon activity was manifested in 100% and 95.3±1.9% of strains correspondingly. The level of adhesive activity in E. cloacae (35.0±7.5%) and anti-complement and adhesive activity in K. pneumoniae consisted 100% and 85.0±5.6% of strains isolated from feces of patients with acute enteric infections reliably (p<0.05) exceeded values in individuals from control group.
Insights
Opportunistic enteric pathogens like Klebsiella pneumoniae and Staphylococcus aureus are increasing. These microbes exhibit significant virulence factors, including strong adhesion and resistance to host defenses, contributing to acute enteric infections.
Area of Science:
- Microbiology
- Infectious Diseases
- Pathogen Analysis
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