Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Binge Eating Disorders01:23

Binge Eating Disorders

816
Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
816
Randomized Experiments01:13

Randomized Experiments

9.4K
The randomization process involves assigning study participants randomly to experimental or control groups based on their probability of being equally assigned. Randomization is meant to eliminate selection bias and balance known and unknown confounding factors so that the control group is similar to the treatment group as much as possible. A computer program and a random number generator can be used to assign participants to groups in a way that minimizes bias.
Simple randomization
Simple...
9.4K
Bulimia Nervosa01:30

Bulimia Nervosa

1.1K
Bulimia nervosa is a complex and severe eating disorder characterized by a cyclical pattern of binge-and-purge eating pattern. It generally involves an episode of binge eating, followed by compensatory behaviors such as vomiting, excessive exercise, laxative use, or fasting, to prevent weight gain. Despite often maintaining a normal weight, individuals with bulimia are intensely preoccupied with their body image and harbor an overwhelming fear of gaining weight. This can contribute to the...
1.1K
Bioavailability Study Design: Healthy Subjects Versus Patients01:15

Bioavailability Study Design: Healthy Subjects Versus Patients

225
Bioavailability studies are essential for evaluating a drug's therapeutic efficacy and understanding its absorption patterns under various physiological conditions. Conducting such studies on target patient populations provides more relevant data by simulating real-world disease states. However, practical challenges often necessitate the use of young, healthy adult volunteers as study subjects.Patients may exhibit altered drug absorption patterns due to the effects of the disease itself,...
225
Group Design02:01

Group Design

11.1K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
11.1K
Anorexia Nervosa01:28

Anorexia Nervosa

2.0K
Anorexia nervosa is a complex and severe eating disorder characterized by an intense fear of weight gain, an unrelenting pursuit of thinness, and a distorted body image. It often leads to dangerously low body weight relative to an individual's age and height. This disorder is marked by significant physical and psychological consequences, making it one of the most life-threatening psychiatric illnesses.
Symptoms and Physical Effects
Individuals with anorexia nervosa commonly exhibit extreme...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Food-related aversion in a female sample of people with anorexia nervosa: Cognitive-behavioural correlates, somatic and subjective anxiety, and early experiences.

Appetite·2022
Same author

Common Genetic Variation and Age of Onset of Anorexia Nervosa.

Biological psychiatry global open science·2022
Same author

Gastrointestinal symptoms, gut microbiome, probiotics and prebiotics in anorexia nervosa: A review of mechanistic rationale and clinical evidence.

Psychoneuroendocrinology·2022
Same author

Risk and protective factors for new-onset binge eating, low weight, and self-harm symptoms in >35,000 individuals in the UK during the COVID-19 pandemic.

The International journal of eating disorders·2022
Same author

A proof-of-concept study for the use of a computerised avatar to embody the eating disorder voice in anorexia nervosa.

Eating and weight disorders : EWD·2022
Same author

Cognitive bias modification training of attention and interpretation to reduce expectations of social rejection in adolescents with eating disorders: A small efficacy randomized controlled trial.

The International journal of eating disorders·2022

Related Experiment Video

Updated: Apr 14, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
04:19

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

Published on: May 10, 2022

4.7K

Self-Help And Recovery guide for Eating Disorders (SHARED): study protocol for a randomized controlled trial.

Valentina Cardi1, Suman Ambwani2, Ross Crosby3

  • 1King's College London, Institute of Psychiatry, Psychological Medicine, Section of Eating Disorders, The Basement, P059, 103 Denmark Hill, London, SE5 8AF, UK. valentina.cardi@kcl.ac.uk.

Trials
|April 18, 2015
PubMed
Summary

This study explores Recovery MANTRA, a guided self-care intervention for anorexia nervosa. Results will assess its feasibility and potential for a larger clinical trial.

More Related Videos

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
06:13

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

2.0K
A Treatment Package without Escape Extinction to Address Food Selectivity
04:23

A Treatment Package without Escape Extinction to Address Food Selectivity

Published on: August 21, 2015

12.2K

Related Experiment Videos

Last Updated: Apr 14, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis
04:19

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

Published on: May 10, 2022

4.7K
Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health
06:13

Author Spotlight: Exploring the Impact of Reduced Resistance Exercise Volume on Metabolic Health

Published on: December 1, 2023

2.0K
A Treatment Package without Escape Extinction to Address Food Selectivity
04:23

A Treatment Package without Escape Extinction to Address Food Selectivity

Published on: August 21, 2015

12.2K

Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Eating Disorder Research

Background:

  • Anorexia nervosa treatment often requires supplementary interventions.
  • The cognitive-interpersonal model highlights key illness maintenance factors.
  • Self-Help And Recovery guide for Eating Disorders (SHARED) trial protocol is described.

Purpose of the Study:

  • To investigate the efficacy of Recovery MANTRA as an adjunct to standard care for anorexia nervosa.
  • To evaluate Recovery MANTRA's impact on weight, eating disorder symptoms, and psychological factors.
  • To determine the feasibility and justification for a larger clinical trial of this intervention.

Main Methods:

  • Randomized controlled trial comparing treatment as usual (TAU) with TAU plus Recovery MANTRA.
  • Primary outcome: change in body weight; Secondary outcomes: eating disorder symptoms, psychological domains.
  • Peer mentor feedback collected to assess their well-being and mentorship impact.

Main Results:

  • Exploratory investigation to determine feasibility for a larger trial.
  • Assesses changes in body weight, eating disorder symptoms, motivation, hope, confidence, mood, flexibility, alliance, and social adjustment.
  • Peer mentor well-being data collected.

Conclusions:

  • Results will inform the justification and feasibility of a larger clinical trial.
  • Recovery MANTRA is an affordable intervention with potential for high reach and scalability.
  • This exploratory study lays groundwork for future anorexia nervosa treatment research.