Related Experiment Video
Updated: Apr 14, 2026

Author Spotlight: A Non-Intubated Video-Assisted Thoracoscopic Surgery with Multimodal Analgesia and Sevoflurane Inhalation Anesthesia
Published on: May 26, 2023
Transtracheal lidocaine injection reduces the anesthetic requirements in brachial plexus surgeries
Sunil Rajan1, Nitu Puthenveettil1, Krishnakumar Thankappan2
1Department of Anaesthesiology, Amrita Institute of Medical Sciences, Kochi, Kerala, India.
Aim:
The purpose of this study was to evaluate the efficacy of transtracheal lidocaine injection to reduce the anesthetic requirements in patients who underwent brachial plexus surgery under general anesthesia.
Settings And Design:
This was a prospective randomized controlled study conducted in 40 consecutive adult patients.
Materials And Methods:
The patients were randomly allotted to two groups of 20 patients each. Group A patients received a transtracheal injection of 4 ml of 2% lidocaine before induction of anesthesia and group B patients did not receive it. The two groups were compared in terms of intraoperative propofol requirements and hemodynamic parameters.
Statistical Analysis Used:
Statistical analysis was done using Student's t-test for independent samples.
Results:
The propofol requirements were significantly less in group A in terms of the number of intraoperative events requiring propofol bolus at various time intervals in 3 h duration (4 vs. 77), the number of patients requiring propofol bolus injections (2 vs. 20), propofol infusion (0 vs. 20), and total propofol requirement (6 vs. 377 mg). After induction, patients in group B showed a statistically significant high heart rate, systolic blood pressure, and mean arterial pressure.
Conclusion:
The present study showed that the group of patients who received transtracheal block with lidocaine had a reduction in the requirement of the induction agent, propofol, and were more stable hemodynamically in the intraoperative period compared to those patients who did not receive transtracheal lidocaine. We conclude that transtracheal injection of lidocaine performed just prior to induction of general anesthesia is an effective alternative to intraoperative propofol infusion when long-acting muscle relaxants are to be avoided.
Related Concept Videos
Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Skeletal Muscle Relaxants: Therapeutic Uses

