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Catalysis02:50

Catalysis

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The presence of a catalyst affects the rate of a chemical reaction. A catalyst is a substance that can increase the reaction rate without being consumed during the process. A basic comprehension of a catalysts’ role during chemical reactions can be understood from the concept of reaction mechanisms and energy diagrams.
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Precipitation Gravimetry01:03

Precipitation Gravimetry

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Precipitation gravimetry is based on converting an analyte into a sparingly soluble precipitate, which is separated by filtration and weighed. An ideal precipitate should be pure, insoluble, of known composition, and easily filtered from the reaction mixture.
In determining nickel by gravimetric analysis, a precipitant of ethanolic dimethylglyoxime is added to a hot nickel salt solution. This is quickly followed by the dropwise addition of dilute ammonia solution until precipitation occurs. A...
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Heterogeneous Catalysis01:22

Heterogeneous Catalysis

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Heterogeneous catalysis involves a catalyst in a different phase from the reactants. It is a process where the catalyst and the reactants are in distinct phases, typically solid and gas or liquid.Most heterogeneous catalysts are metals, metal oxides, or acids. The list includes transition metals like iron (Fe), cobalt (Co), nickel (Ni), palladium (Pd), platinum (Pt), chromium (Cr), manganese (Mn), tungsten (W), silver (Ag), and copper (Cu). These metals possess partially vacant d orbitals that...
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Updated: Apr 14, 2026

Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area
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Chemical Precipitation Method for the Synthesis of Nb2O5 Modified Bulk Nickel Catalysts with High Specific Surface Area

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A modular, air-stable nickel precatalyst.

Jason D Shields1, Erin E Gray1, Abigail G Doyle1

  • 1Department of Chemistry, Princeton University, Princeton, New Jersey 08544, United States.

Organic Letters
|April 18, 2015
PubMed
Summary
This summary is machine-generated.

A new nickel complex, [(TMEDA)Ni(o-tolyl)Cl], is an effective precatalyst for various reactions. Its versatile ligand compatibility and tunable activation mechanisms offer broad catalytic applications.

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Area of Science:

  • Organometallic Chemistry
  • Catalysis

Background:

  • Nickel complexes are crucial in catalysis.
  • Developing stable and versatile precatalysts is essential for advancing chemical transformations.

Purpose of the Study:

  • To synthesize and characterize a novel, air-stable nickel precatalyst.
  • To evaluate its catalytic activity in diverse nickel-catalyzed reactions.
  • To investigate its activation pathways.

Main Methods:

  • Synthesis of [(TMEDA)Ni(o-tolyl)Cl] complex.
  • Testing its efficacy as a precatalyst in various transformations.
  • Preliminary mechanistic studies.

Main Results:

  • [(TMEDA)Ni(o-tolyl)Cl] was synthesized as an air-stable, crystalline solid.
  • The complex demonstrated effectiveness as a precatalyst in multiple nickel-catalyzed reactions.
  • The lability of the TMEDA ligand allows for diverse ligand substitution (phosphines, diimines, NHCs).
  • Mechanistic studies indicated activation via Ni-B or Ni-Ni transmetalation, dependent on reaction conditions.

Conclusions:

  • [(TMEDA)Ni(o-tolyl)Cl] is a versatile and stable nickel precatalyst.
  • Its adaptable nature and tunable activation modes make it promising for various catalytic applications.