Related Experiment Video
Updated: Apr 14, 2026

04:14
Author Spotlight: In Vivo Assessment of Thyroid Hormone Disruption Using the THAI Mouse Model
Published on: October 6, 2023
1.4K
Out of the blue! Thyroid crisis
Mrunalini Parasa1, Bala Kusuma Kumari Chinthakunta1, Nagendra Nath Vemuri1
1Department of Anaesthesiology, NRI Medical College, Guntur, Andhra Pradesh, India.
Anesthesia, Essays and Researches
|April 18, 2015
Summary
Undiagnosed hyperthyroidism can cause dangerous heart rhythm problems, especially during surgery. Early recognition and treatment of thyroid storm are crucial for patient survival.
Area of Science:
- Cardiology
- Endocrinology
- Anesthesiology
Background:
- Cardiovascular complications in undiagnosed hyperthyroidism present diagnostic challenges.
- Thyroid storm, a severe manifestation of hyperthyroidism, requires prompt management.
Observation:
- A 45-year-old male presented with atrial fibrillation and left ventricular dysfunction prior to emergency surgery.
- Thyromegaly was noted during central venous catheterization, raising suspicion for thyroid dysfunction.
Findings:
- Echocardiography showed left ventricular dysfunction (ejection fraction 47%) without structural abnormalities.
- The patient's cardiovascular status was attributed to undiagnosed hyperthyroidism, leading to thyroid crisis.
- Successful management of the thyroid crisis was achieved.
Implications:
- Highlights the importance of considering thyroid dysfunction in patients with unexplained cardiac issues, particularly perioperatively.
- Emphasizes the need for timely diagnosis and aggressive management of thyroid storm to prevent fatal outcomes.
- Underscores the critical role of multidisciplinary collaboration in managing complex endocrine-cardiac emergencies.
Related Concept Videos
Synthesis and Regulation of Thyroid Hormones
9.4K
Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
9.4K
The Thyroid Gland
9.1K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
9.1K
Functions of Thyroid Hormones
7.0K
The thyroid hormone (TH) plays a pivotal role in the intricate orchestration of physiological processes, exerting profound effects on development, metabolism, and homeostasis throughout different life stages.
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
TH is indispensable for the normal development and maturation of the skeletal, muscular, and nervous systems during fetal and childhood growth. It facilitates bone mineral turnover and regulates protein synthesis in developing tissues, contributing significantly to overall growth and...
7.0K
Major Hormones and Their Functions
3.5K
Hormones, the biochemical messengers produced by endocrine glands, are pivotal in regulating bodily functions and maintaining homeostasis. Each hormone's balance is crucial; imbalances can lead to significant physiological disruptions. Major hormones include oxytocin, cortisol, epinephrine, estrogen, testosterone, thyroxine, growth hormone, insulin, and glucagon.
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
Oxytocin, produced in the hypothalamus and released by the pituitary gland, plays a role in social bonding, childbirth, and...
3.5K
Acute Coronary Syndrome V: Nursing Management
579
Nursing Assessment:Nursing management of acute coronary syndrome (ACS) involves taking the patient's history, focusing on primary complaints such as chest pain, dyspnea, and excessive sweating (diaphoresis), as well as other symptoms like back or jaw pain, nausea, vomiting, palpitations, dizziness, and fatigue. The nurse also reviews the patient's history of cardiac events, risk factors such as hypertension, diabetes, smoking, family history, and current medications.In the objective assessment,...
579
Hypertension I: Introduction
1.3K
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
1.3K

