Accuracy of administrative claims data to identify dose specific rotavirus vaccination information: Implications for studies of vaccine safety
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Published on: January 28, 2019
Scott C Quinlan1, Stephan Lanes1, Crystal N Holick1
1HealthCore, Inc., 800 Delaware Avenue, Fifth Floor, Wilmington, DE 19801, United States.
Insights
Administrative claims data show inaccuracies in vaccine records for RotaTeq (RV5) first doses. Approximately 13% of recorded RV5 vaccinations had errors in dose number or administration date, impacting data reliability.
Area of Science:
- Vaccinology
- Health Informatics
- Pediatric Public Health
Background:
- Vaccine administration data in claims databases often lacks verified accuracy.
- Reliable vaccine records are crucial for public health surveillance and research.
Purpose of the Study:
- To assess the accuracy of RotaTeq (RV5) vaccine administration information in administrative claims data.
- To determine the extent of discrepancies between claims data and medical records for infant vaccinations.
Main Methods:
- A retrospective cohort study was performed using the HealthCore Integrated Research Database(SM).
- Infants receiving at least one RotaTeq (RV5) dose within their first year were identified.
- Medical records were sampled to validate vaccine administration dates and dose information.
Main Results:
- 169,560 infants received at least one RV5 dose.
- Validation of medical records for 85 infants revealed that 74 (87.1%) had corresponding RV5 vaccination entries.
- Discrepancies in administration date or dose number were noted for a subset of records.
Conclusions:
- Administrative claims data demonstrated inaccuracies for approximately 13% of RotaTeq (RV5) first doses.
- These findings highlight potential limitations in using claims data for precise vaccine administration tracking.
Background:
The accuracy of vaccine administration information recorded in administrative claims databases is uncertain.
Methods:
We conducted a retrospective cohort study using the HealthCore Integrated Research Database(SM) among infants who received at least 1 RotaTeq (RV5) dose during the first year of life between February 1, 2006 and November 30, 2012 and were enrolled in the health plan at birth. We reviewed medical records for a sample of infants to validate vaccine administration information.
Results:
We identified 169,560 infants who received at least 1 RV5 dose. Medical records were obtained for 85 infants, of which 74 (PPV1 87.1%; 95% CI 78.0-93.4%) had a corresponding first RV5 vaccination in the medical record with the same or similar administration date.
Conclusions:
Administrative claims contained inaccuracies in dose number or administration date for 13% of RV5 first doses identified.
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