Related Experiment Video
Updated: Apr 14, 2026

Anesthesia and Intubation of Preadolescent Mouse Pups for Cardiothoracic Surgery
Published on: June 2, 2022
Safe Anesthesia For Every Tot - The SAFETOTS initiative
Markus Weiss1, Laszlo Vutskits, Tom G Hansen
1aFaculty of Medicine, University of Zurich bDepartment of Anaesthesia, University Children's Hospital Zurich, Zurich, Switzerland cDepartment of Anesthesiology, Pharmacology and Intensive Care, University Hospital of Geneva, Geneva dDepartment of Anaesthesia & Intensive Care, Paediatric Section, Odense University Hospital eClinical Institute - Anaesthesiology, University of Southern Denmark, Odense, Denmark fSchool of Medicine and Dentistry, University of Aberdeen, Royal Aberdeen Children's Hospital, Scotland, UK.
Insights
The Safe Anesthesia For Every Tot initiative defines the safe conduct of pediatric anesthesia. It provides guidance on quality markers and aims to improve perioperative outcomes in children through better regulations and training.
Area of Science:
- Pediatric Anesthesia
- Patient Safety
- Healthcare Quality Improvement
Background:
- The safe use of anesthesia in children is not well-defined.
- There is a need to focus on the safe conduct of pediatric anesthesia.
- Perioperative risks and cerebral morbidity in young children are significant concerns.
Purpose of the Study:
- To define and focus on the 'safe conduct of pediatric anesthesia'.
- To establish guidance on quality markers for anesthesia care in children.
- To address gaps in regulations, teaching, and research related to pediatric anesthesia.
Main Methods:
- The establishment of the Safe Anesthesia For Every Tot (SAFETOTS) initiative.
- Focus on defining the 'who, where, when, and how' of pediatric anesthesia.
- Development of guidance on quality markers for anesthesia care.
Main Results:
- The SAFETOTS initiative aims to provide guidance on quality markers for pediatric anesthesia.
- National regulations for 'who, where, when, and how' are required for improved perioperative outcomes.
- Improvement in teaching, training, education, and supervision is a primary goal.
Conclusions:
- The SAFETOTS initiative provides a framework for the safe conduct of pediatric anesthesia.
- Addressing perioperative risks, cerebral morbidity, and regulatory/educational gaps is crucial.
- Defining key aspects of pediatric anesthesia ensures a higher standard of care for vulnerable children.
Purpose Of Review:
The term 'safe use of anesthesia in children is ill-defined and requires definition of and focus on the 'safe conduct of pediatric anesthesia'.
Recent Findings:
The Safe Anesthesia For Every Tot initiative (www.safetots.org) has been set up during the last year to focus on the safe conduct of pediatric anesthesia. This initiative aims to provide guidance on markers of quality anesthesia care. The introduction and implementation of national regulations of 'who, where, when and how' are required and will result in an improved perioperative outcome in vulnerable children. The improvement of teaching, training, education and supervision of the safe conduct of pediatric anesthesia are the main goals of the safetots.org initiative.
Summary:
This initiative addresses the well known perioperative risks in young children, perioperative causes for cerebral morbidity as well as gaps in regulations, teaching and research. Defining the 'who', 'where', 'when' and 'how' in this context provides the framework for the safe conduct of pediatric anesthesia.
Related Concept Videos
Parenteral Anesthetics: Overview
Inhalational Anesthetics: Overview
General Anesthesia: Overview
General anesthesia induces unconsciousness in the whole body, while the others target specific areas or sensations. It is administered to minimize adverse effects, maintain...
Stages of General Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...

