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Salmonella Typhi meningitis in a 9-year old boy with urinary schistosomiasis: a case report
Flora Chacha1, Stephen E Mshana2, Mariam M Mirambo3
1Department of Pediatric and child Health Weill Bugando School of Medicine, Catholic University of Health and Allied Sciences, Mwanza, Tanzania. chachaf733@gmail.com.
Background:
Cases of Salmonella Typhi meningitis have been rarely reported in infants. There are few documented cases of persistent salmonella bacteraemia in patients with schistosomiasis. A presented case highlights the importance of broadening the list of pathogens that can cause meningitis among older children in schistosomiasis endemic regions.
Case Presentation:
The reported case is of a 9-year old sukuma-black African boy referred to Bugando Medical Centre with complaints of fever, abdominal pain, headache and generalized body weakness. On examination; the child was febrile (39°C) with neck stiffness and distended abdomen. Cerebrospinal fluid culture was positive for Salmonella Typhi. In addition on urine sediments microscopy, Schistosoma haematobium eggs were seen. The child improved clinically on ceftriaxone and praziquantel, and was discharged 3 weeks after admission.
Conclusion:
Complicated persistent salmonella infection should be considered in schistosomiasis endemic areas. More research should be done to confirm the association between salmonella infections and urinary schistosomiasis.
Insights
Salmonella Typhi meningitis is rare in infants but can occur in children with schistosomiasis. This case highlights the need to consider Salmonella Typhi in febrile children in endemic regions.
Area of Science:
- Infectious Diseases
- Parasitology
- Pediatrics
Background:
- Salmonella Typhi meningitis is uncommon in infants.
- Persistent Salmonella bacteraemia is rarely documented in individuals with schistosomiasis.
- This case underscores the need to consider a broader range of pathogens for meningitis in endemic areas.
Observation:
- A 9-year-old boy presented with fever, headache, and abdominal pain.
- Cerebrospinal fluid culture confirmed Salmonella Typhi infection.
- Microscopy revealed Schistosoma haematobium eggs in urine, indicating co-infection.
Findings:
- The patient exhibited clinical improvement with ceftriaxone and praziquantel treatment.
- The case demonstrates a rare instance of Salmonella Typhi meningitis and persistent bacteraemia in a child with urinary schistosomiasis.
- Successful treatment was achieved with antibiotics and antiparasitic medication.
Implications:
- Complicated Salmonella infections should be considered in schistosomiasis-endemic regions.
- Further research is warranted to elucidate the association between Salmonella infections and urinary schistosomiasis.
- This case highlights the importance of considering co-infections in clinical practice.
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