Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Conduction velocity study in type 1 diabetic patients.

F Meli1, F Cardella, D Raimondo

  • 1Department of Paediatrics, University of Palermo, Italy.

Acta Neurologica Scandinavica
|November 1, 1989
PubMed
Summary

Hyperglycemia in type 1 diabetes can impair peripheral nerve function, specifically sensory nerve conduction. Lowering blood sugar levels improved nerve conduction, suggesting metabolic control is key for preventing diabetic neuropathy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Premedication with Lugol's solution in total thyroidectomy for graves' disease and toxic multinodular goiter: is it still indicated?

Updates in surgery·2025
Same author

Impact of Sex on Infection Risk in Patients with Systemic Lupus Erythematosus.

Bioengineering (Basel, Switzerland)·2025
Same author

Comparison between learning curves of robot-assisted and laparoscopic surgery in gynaecology: a systematic review.

Facts, views & vision in ObGyn·2024
Same author

Glucose metrics and device satisfaction in adults with type 1 diabetes using different treatment modalities: a multicenter, real-world observational study.

Acta diabetologica·2024
Same author

The anatomy of the pelvic plexus in female cadavers: implications for retroperitoneal nerve-sparing surgery.

Facts, views & vision in ObGyn·2024
Same author

SARS-CoV-2 infection in adult liver transplantation recipients: a systematic review of risk factors for mortality and immunosuppression role.

European review for medical and pharmacological sciences·2023

Area of Science:

  • Neurology
  • Endocrinology
  • Metabolic Disorders

Background:

  • Diabetic neuropathy is a common complication of diabetes.
  • The precise role of metabolic abnormalities, particularly hyperglycemia, in its development is debated.
  • Understanding these mechanisms is crucial for effective management.

Purpose of the Study:

  • To investigate peripheral nerve function in children with type 1 diabetes.
  • To determine the influence of hyperglycemia on nerve conduction over one year.
  • To explore the relationship between glycemic control and neurophysiological changes.

Main Methods:

  • A one-year prospective neurophysiological study.
  • Involved 30 children (ages 2-16) with type 1 diabetes.
  • Assessed glycosylated hemoglobin, peroneal motor, and tibial motor/sensory nerve conduction thrice.

Related Experiment Videos

Main Results:

  • Significant sensory latency delay was observed in diabetic patients compared to controls.
  • Sensory conduction slowing correlated strongly with glycosylated hemoglobin levels.
  • Improvements in nerve conduction were noted with reduced hyperglycemia.

Conclusions:

  • Hyperglycemia negatively impacts peripheral nerve conduction in type 1 diabetes.
  • Glycemic control is a critical factor in the progression of diabetic neuropathy.
  • Interventions aimed at reducing hyperglycemia may help preserve nerve function.