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Chronic rhinosinusitis: an under-researched epidemic.
1Division of Otolaryngology - Head and Neck Surgery, Department of Surgery, University of Calgary, Richmond Road Diagnostic and Treatment Centre, 1820 Richmond Rd., SW, T2T 5C7, Calgary, Alberta, Canada. Lukerudmik@gmail.com.
Summary
Research on chronic rhinosinusitis (CRS) lags significantly behind asthma and diabetes. Despite similar impacts, CRS receives less research funding and publication volume, highlighting a need for increased prioritization.
Area of Science:
- Medical research
- Inflammatory diseases
- Public health
Background:
- Chronic rhinosinusitis (CRS) is a widespread inflammatory condition affecting quality of life and productivity.
- Understanding research volume disparities can reveal prioritization issues.
Purpose of the Study:
- To compare the publication volume of research on CRS with asthma and diabetes mellitus (DM).
- To identify research gaps and inform prioritization for CRS.
Main Methods:
- Systematic review of Ovid MEDLINE (1970-2014).
- Compared publication volumes for CRS, asthma, and DM.
- Subgroup analysis of publication types (RCTs, reviews, economic evaluations) using chi-square tests.
Main Results:
- Vast disparities in research volume: CRS (7,962) vs. asthma (136,652) vs. DM (337,411).
- Annual publication disparities remained consistent over 45 years.
- Increasing CRS research volume, but still significantly lower than asthma and DM.
Conclusions:
- Significant under-researching of CRS compared to asthma and DM.
- Similar prevalence, quality of life impact, and economic burden warrant increased CRS research.
- Urgent need to prioritize and increase research investment in chronic rhinosinusitis.
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