Related Experiment Video
Updated: Apr 14, 2026
05:10
Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
1.5K
Examining the relationship between obesity and cognitive function: a systematic literature review
Christina Prickett1, Leah Brennan2, Rene Stolwyk3
1School of Psychological Sciences, Faculty of Medicine, Nursing & Health Sciences, Monash University, Australia; Centre for Obesity Research and Education, Faculty of Medicine, Nursing & Health Sciences, Monash University, Australia.
Obesity Research & Clinical Practice
|April 20, 2015
Summary
Obesity may impact cognitive function in adults, but more research is needed. Current studies show cognitive deficits in obese individuals, yet methodological limits prevent confirming an independent link between obesity and cognitive decline.
Area of Science:
- Neuroscience
- Public Health
- Gerontology
Background:
- Rising rates of obesity and dementia present a significant public health challenge.
- Existing research suggests a link between obesity and dementia, but the independent effect of obesity on cognition is unclear.
- Domain-specific cognitive deficits in obese adults require systematic comparison.
Purpose of the Study:
- To systematically review evidence on domain-specific cognitive deficits in obese adults (BMI > 30 kg/m²).
- To assess if studies establish an independent relationship between obesity and cognition, controlling for comorbidities.
Main Methods:
- Systematic literature review of 17 articles.
- Inclusion criteria: obese adults (18-65 years), BMI > 30 kg/m².
- Assessment of cognitive domains and control for comorbidities.
Main Results:
- Obese adults exhibited impairments across multiple cognitive domains, including attention, memory, and decision-making.
- Significant methodological limitations were identified in the reviewed studies.
- Insufficient evidence exists to confirm a reliable independent association between mid-life obesity and cognitive impairment.
Conclusions:
- Cognitive impairments are evident in obese adults, but methodological limitations hinder definitive conclusions.
- Further research is recommended to address limitations and clarify the independent relationship between mid-life obesity and cognition.
- Improved understanding will aid in developing strategies for identifying, preventing, and treating cognitive decline in obese populations.
