Imaging of Tumor Angiogenesis for Radiologists--Part 1: Biological and Technical Basis
Roberto García-Figueiras1, Anwar R Padhani2, Ambros J Beer3
1Department of Radiology, Hospital Clínico Universitario de Santiago de Compostela, Santiago de Compostela, Spain.
Abstract:
Angiogenesis is a key cancer hallmark involved in tumor growth and metastasis development. Tumor angiogenesis is the process whereby new blood vessels are formed to supply nutrients and oxygen to support the growth of tumors. This article reviews the biological basis behind imaging features and the different imaging modalities used to assess the status of tumor neovasculature in vivo at different scales: structural, functional, and molecular.
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