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Updated: Apr 14, 2026
Author Spotlight: Improving the Production of Self-Assembling Fibers and Peptide Hydrogels for Superior Biocompatibility
Published on: September 6, 2024
Alignment of nanostructured tripeptide gels by directional ultrasonication
Charalampos G Pappas1, Pim W J M Frederix, Tapiwa Mutasa
1Advanced Science Research Center (ASRC) and Hunter College, City University of New York, New York, NY 10031, USA. Rein.Ulijn@asrc.cuny.edu.
Abstract:
We demonstrate an in situ ultrasonic approach to influence self-assembly across the supramolecular to micron length scales, showing enhancement of supramolecular interactions, chirality and orientation, which depends on the peptide sequence and solvent environment. This is the first successful demonstration of using oscillating pressure waves to generate anisotropic organo- and hydrogels consisting of oriented tripeptides structures.
