Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

4.0K
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
4.0K
Inflammatory Bowel Disease I: Ulcerative Colitis01:27

Inflammatory Bowel Disease I: Ulcerative Colitis

1.5K
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
1.5K
Inflammatory Bowel Disease II: Crohn's Disease01:30

Inflammatory Bowel Disease II: Crohn's Disease

1.6K
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
1.6K
Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

888
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
888
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

950
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
950
Histology of the Small Intestine01:27

Histology of the Small Intestine

5.1K
The small intestine exhibits a unique histological structure that significantly enhances its function in digestion and nutrient absorption. These structures include circular folds, villi, and various specialized cells that collectively facilitate the digestion of food.
The intestinal lining features transverse folds called circular folds, each housing fingerlike projections known as intestinal villi. These villi are covered by a layer of simple columnar epithelium, also referred to as...
5.1K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Preoperative Soluble AXL in Plasma Predicts Futility of Resecting Pancreatic Ductal Adenocarcinoma.

Current oncology (Toronto, Ont.)·2026
Same author

Effective allogeneic natural killer cell therapy for pancreatic adenocarcinoma avails conserved activating receptors and evades HLA I-driven inhibition.

Journal for immunotherapy of cancer·2026
Same author

Peri-tumoural lymphocyte neighbourhoods predict longer survival in pancreatic ductal adenocarcinoma.

Frontiers in immunology·2025
Same author

Claudin 18 (43-14A clone) expression in pancreatic ductal adenocarcinoma: Assessment of a potential clinical biomarker for zolbetuximab therapy.

Translational oncology·2025
Same author

Canadian Consensus Recommendations for Predictive Biomarker Testing in Gastric and Gastroesophageal Junction Adenocarcinoma.

Current oncology (Toronto, Ont.)·2024
Same author

Glypican-3 and Cytokeratin-19 Expression in Pancreatic Cancer in a Canadian Population.

Journal of clinical medicine·2024
Same journal

TROP2 immunoreactivity in pulmonary large cell neuroendocrine carcinoma.

Histopathology·2026
Same journal

Malignant adenomyoepithelioma of the breast: seven cases illustrating morphological diversity and diagnostic challenges.

Histopathology·2026
Same journal

A CRX-positive RB1-deficient bone tumour with a retinoblastoma-like DNA methylation profile.

Histopathology·2026
Same journal

Perivascular epithelioid cell tumours of the genitourinary tract: clinicopathological features and molecular landscape.

Histopathology·2026
Same journal

Navigating diagnostic challenges in low-grade spindle cell lesions of the breast: a retrospective review.

Histopathology·2026
Same journal

Neoplastic transformation of sporadic gastric hyperplastic polyps: a systematic review and meta-analysis of risk factors and clinicopathological features.

Histopathology·2026
See all related articles

Related Experiment Video

Updated: Apr 14, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K

Ileitis associated with Meckel's diverticulum.

Claire M Hamilton1, Thomas Arnason1

  • 1Division of Anatomical Pathology, Queen Elizabeth II Health Sciences Centre and Dalhousie University, Halifax, NS, Canada.

Histopathology
|April 21, 2015
PubMed
Summary
This summary is machine-generated.

Inflammation near Meckel's diverticulum is common but often not Crohn's disease. Short segment ileitis in adults with Meckel's diverticulum typically resolves without progression to Crohn's disease.

Keywords:
Crohn's diseaseMeckel's diverticulumchronic active enteritisileitis

More Related Videos

Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

10.1K
Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.7K

Related Experiment Videos

Last Updated: Apr 14, 2026

Multimodality Diagnosis of Mesenteric Ischemia
05:07

Multimodality Diagnosis of Mesenteric Ischemia

Published on: July 21, 2023

1.4K
Ileectomy-induced Bile Overaccumulation in Mouse Intestine
06:55

Ileectomy-induced Bile Overaccumulation in Mouse Intestine

Published on: August 21, 2017

10.1K
Chronic Salmonella Infection Induced Intestinal Fibrosis
08:40

Chronic Salmonella Infection Induced Intestinal Fibrosis

Published on: September 22, 2019

7.7K

Area of Science:

  • Gastroenterology
  • Surgical Pathology
  • Digestive Diseases

Background:

  • Meckel's diverticulum can present with ileitis, raising suspicion for Crohn's disease.
  • Previous reports suggest ileitis may stem from gastric heterotopia or be linked to Crohn's disease.
  • The association between Meckel's diverticulum, ileitis, and Crohn's disease requires further investigation.

Purpose of the Study:

  • To determine the incidence and histomorphology of ileitis associated with Meckel's diverticulum.
  • To evaluate the clinical follow-up of patients with Meckel's diverticulum-associated ileitis.
  • To differentiate ileitis near Meckel's diverticulum from Crohn's disease.

Main Methods:

  • Review of medical records and histological slides from 48 surgical resections for Meckel's diverticulum.
  • Analysis of inflammatory changes in the small intestine adjacent to the diverticulum.
  • Clinical follow-up of patients with identified ileitis.

Main Results:

  • Nine of 48 patients exhibited significant inflammatory changes near the diverticulum.
  • Two patients had Crohn's disease with inflammation distant from the diverticulum.
  • Five patients had short-segment ileitis with specific histological features, two with gastric heterotopia, and none developed Crohn's disease on follow-up.

Conclusions:

  • Short segment ileitis adjacent to Meckel's diverticulum is relatively common.
  • This type of ileitis is not necessarily indicative of Crohn's disease.
  • Histological features and clinical course help distinguish Meckel's diverticulum-associated ileitis from Crohn's disease.