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Adenocarcinoma and wood
S Schraub1, M Belon-Leneutre, M Mercier
1Cancer Registry of Doubs, Hôpital Jean Minjoz, Besancon, France.
American Journal of Epidemiology
|December 1, 1989
Summary
This study investigated if wood dust exposure causes bronchial adenocarcinoma. Researchers found no significant link between occupational wood dust exposure and lung adenocarcinoma, suggesting it is not a primary risk factor.
Area of Science:
- Occupational Health
- Epidemiology
- Oncology
Background:
- Adenocarcinoma of the facial sinuses is linked to wood dust exposure.
- Similarities between sinus and tracheobronchial mucosa suggest a potential link between wood dust and bronchial adenocarcinoma.
Purpose of the Study:
- To investigate the hypothesis that wood dust exposure is a risk factor for bronchial adenocarcinoma.
Main Methods:
- A case-control study was conducted using lung adenocarcinoma cases from the Doubs region, France (1978-1985).
- Matched random population controls were selected.
- Occupational exposure and tobacco consumption were assessed via questionnaire for 53 cases and 160 controls.
Main Results:
- No significant difference in wood dust exposure was found between lung adenocarcinoma cases and controls.
- The crude relative risk (odds ratio) for wood dust exposure was 1.06.
- Adjustment for tobacco consumption did not alter the risk estimate.
Conclusions:
- Wood dust exposure does not appear to be an occupational risk factor in the development of bronchial adenocarcinoma.
- The postulated link between wood dust and lung adenocarcinoma was not supported by this study.