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Post-traumatic Stress Disorder01:27

Post-traumatic Stress Disorder

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Post-traumatic stress disorder (PTSD) is a psychiatric condition that arises following exposure to traumatic events such as natural disasters, forced displacement, or severe accidents. It significantly impairs individuals' ability to cope with daily activities and disrupts their emotional and psychological equilibrium.
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events,...
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Traumatic Memory01:20

Traumatic Memory

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Emotionally traumatic events often lead to memories that are exceptionally vivid and enduring, sometimes persisting with remarkable clarity throughout an individual's life. A classic example of this phenomenon is a person who survives a car accident. Even years later, they may recall every detail of the event with startling accuracy — the screeching of the tires, the jarring impact, and the acrid smell of burning rubber. Such vividness contrasts sharply with how an individual...
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Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

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Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
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Hypothalamic-Pituitary Axis01:37

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The response to stress—be it physical or psychological, acute or chronic—involves activation of the Hypothalamic-Pituitary-Adrenal (HPA) axis. The HPA axis is part of the neuroendocrine system because it involves both neuronal and hormonal communication. Its function is to regulate homeostatic systems—metabolic, cardiovascular, and immune—providing the necessary means to respond to a stressor.
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Psychological Responses to Stress01:20

Psychological Responses to Stress

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Psychological responses to stress encompass the various cognitive and emotional reactions individuals experience when faced with challenging or threatening situations, such as a job loss. Prolonged exposure to stressors can disturb emotional balance, increasing negative emotions (e.g., anxiety and sadness) and diminishing positive emotions (e.g., joy and satisfaction). These persistent emotional shifts are associated with an increased risk of both physical illness and mental health issues, such...
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Introduction to Stress and Lifestyle01:27

Introduction to Stress and Lifestyle

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Stress is a multifaceted response to events perceived as challenging or threatening, highlighting physical, emotional, cognitive, and behavioral reactions. Physically, stress can lead to fatigue, sleep disruptions, and various health issues such as frequent colds, chest pains, and nausea. Emotionally, it can manifest as anxiety, depression, irritability, and anger triggered by both minor and major life events. Cognitively, it may result in difficulty in concentration, memory, and...
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Related Experiment Video

Updated: Apr 14, 2026

Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure
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Simultaneous Application of Transcranial Direct Current Stimulation during Virtual Reality Exposure

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Neural communication in posttraumatic growth.

Samantha L Anders1, Carly K Peterson, Lisa M James

  • 1Brain Sciences Center (11B), Minneapolis Veterans Affairs Health Care System, One Veterans Drive, Minneapolis, MN, 55417, USA.

Experimental Brain Research
|April 21, 2015
PubMed
Summary
This summary is machine-generated.

Posttraumatic growth (PTG) involves positive changes after trauma. Healthy individuals show neural changes linked to PTG, but veterans with PTSD do not, suggesting altered neural adaptation.

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Area of Science:

  • Neuroscience
  • Psychology
  • Trauma Studies

Background:

  • Posttraumatic growth (PTG) is common in trauma survivors.
  • Neural mechanisms underlying PTG require further investigation.
  • Understanding PTG in veterans with PTSD is crucial.

Purpose of the Study:

  • To investigate the neural correlates of PTG in veterans.
  • To compare neural activity between veterans with PTSD and controls.
  • To examine the relationship between PTG and neural synchrony.

Main Methods:

  • Task-free magnetoencephalography (MEG) was used.
  • 106 veterans with PTSD and 193 veteran controls participated.
  • Diagnostic interviews and PTG measures were administered.

Main Results:

  • Global synchronous neural interactions (SNIs) decreased with higher PTG in controls.
  • This modulation was absent in veterans with PTSD.
  • The effect was localized to the medial prefrontal cortex and local networks.

Conclusions:

  • Neural adaptation may play a role in healthy PTG.
  • Veterans with PTSD may exhibit altered neural responses to trauma.
  • Findings highlight differences in neural processing between controls and PTSD patients.