Related Experiment Video
Updated: Apr 14, 2026

Ole Isacson: Development of New Therapies for Parkinson's Disease
Published on: April 29, 2007
Herbal medicine treatment for drug-induced parkinsonism
Young-Ho Shim1, Joo-Young Park, Won-Woo Choi
11 Department of Cardiology and Neurology, College of Korean Medicine, Kyung Hee University , Seoul, Korea.
Objectives:
To evaluate the role of herbal medicine in drug-induced parkinsonism (DIP) and identify an optimal treatment approach.
Design:
Retrospective review of DIP cases treated with herbal medicine.
Settings/Location:
The Parkinson's clinic at Kyung Hee Traditional Korean Medicine Hospital, Korea.
Patients:
Twenty-one patients whose clinical outcome and offending drug could be identified.
Outcome Measures:
Clinical features, treatments, and outcomes and summarized the clinical course and treatment in each case.
Results:
Twelve patients had levosulpiride-induced parkinsonism and 9 had parkinsonism induced by another drug. The offending drugs were discontinued in all patients, and all patients received herbal medications during treatment. Nine of 12 patients with parkinsonism from levosulpiride and 4 of 9 patients with parkinsonism from other drugs had complete reversal of symptoms. The most frequently used herbal formula was Ukgansan (Yigansan). DIP in the levosulpiride group tended to improve faster with herbal medicine, and the percentage of improvement was higher.
Conclusions:
Optimal herbal medicine treatments chosen after a careful history and evaluation for risk factors may be helpful in reversing DIP.
More Related Videos
11:44Cellular Membrane Affinity Chromatography Columns to Identify Specialized Plant Metabolites Interacting with Immobilized Tropomyosin Kinase Receptor B
Published on: January 19, 2022
05:51Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
Published on: October 14, 2021
Related Concept Videos
Parkinson's Disease: Treatment
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease: Overview
Drug Therapy
Antianxiety Medications
Alzheimer's Disease: Treatment
Pharmaceutical Poisoning: Treatment Strategies
Psychosis: Goals of Pharmacotherapy