Related Experiment Video
Updated: Apr 14, 2026

Midface Hypoplasia and Cranial Base Morphology in Syndromic Craniosynostosis: A Comparative Analysis Study Using a Predictive Regression Model
Published on: November 4, 2025
Age-related changes in the location of the mandibular and mental foramen in children with Mongoloid skeletal pattern
1Department of Paediatric Dentistry and Orthodontics, Faculty of Dentistry, University of Malaya, Kuala Lumpur, Malaysia.
Aim:
To observe age-related changes in the locations of mandibular foramen (MF) and mental foramen (mf) using dental panoramic tomographs (DPTs).
Methods:
Ethical approval was obtained for this retrospective study. Location of MF was related to the ramus and occlusal plane, while mf to (i) erupted primary molars (ii) unerupted premolar tooth germs (iii) vertical height at the body of the mandible.
Results:
One hundred and sixty-five DPTs were obtained from children with Mongoloid skeletal pattern. The ethnic composition was 112 Malays and 53 Chinese children (Willems dental age = 5.2-16.0 years). At the horizontal plane, MF remained constant at middle mid-quadrant of the ramus (88 %) and vertical plane; 68 % located below and 40 % above the occlusal plane. At age 9 years and above, there was a significant tendency for MF to be located at the level of occlusal plane. The most common location of mf was related to (i) erupted primary molars, mesial root of second primary molar (38 %); (ii) unerupted premolars tooth germs, between the apices of first and second premolar (44 %); and (iii) proportional vertical height to the mandible, middle third (52 %). At age 11 years and above, a significant tendency of mf to be located at the middle third of the body of mandible was observed.
Conclusions:
With advancing age and growth, the position of MF remained constant at the ramus with tendency to move from below to at the level of occlusal plane, while mf moved distally and inferiorly.
Related Concept Videos
Changes in the Appendicular Skeleton with Age
Initially, the limb buds consist of a core of mesenchyme covered by a layer of ectoderm. The ectoderm at the end of the limb bud thickens to form a narrow crest called the apical ectodermal ridge. This ridge stimulates the underlying...
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Sutures of the Skull
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into ...
Cranial Bones: Lateral View
The temporal bone forms the lower lateral side of the skull. The temporal bone is subdivided into several regions. The flattened upper portion is the squamous portion of the temporal bone. Below this area and projecting anteriorly is the zygomatic process of the temporal bone, which forms the posterior portion of the zygomatic arch. Posteriorly is the mastoid portion of the temporal bone. Projecting...
Bone Formation by Endochondral Ossification

