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Synthesis of new DNA molecules is carried out by the enzyme DNA polymerase, which adds nucleotides on the daughter strand complementary to the template DNA strand. DNA polymerase has a higher affinity to add the correct base and ensures fidelity during DNA replication. Furthermore,  it exhibits proofreading activity during replication, using an exonuclease domain that cuts off incorrect nucleotides from the nascent DNA strand.
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Author's Reply

Wietse J Eshuis1, Olivier R Busch, Dirk J Gouma

  • 1Department of Surgery Academic Medical Center Amsterdam, The Netherlands.

Annals of Surgery
|April 21, 2015
PubMed
Summary

No abstract available in PubMed .

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