Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Bones of the Lower Limb: Femur and Patella

Bones of the Lower Limb: Femur and Patella

The femur is the body's longest and strongest bone spanning the thigh region. Its head articulates with the acetabulum of the hip bone to form the hip joint. A minor indentation on the medial side of the femoral head, called the fovea capitis, serves as the site of attachment for the ligament of the head of the femur. This weak ligament spans the femur and acetabulum and supports the hip joint. The narrowed region below the head is the neck of the femur. The inclination angle between the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mechanical axis image quality of the EOS imaging system compared to digital radiographs.

Skeletal radiology·2026

Same author

Development of an in silico hybrid model for scoliosis correction using Ansys Motion.

Computer assisted surgery (Abingdon, England)·2026

Same author

Exploring the effect of different neural strategies on the knee joint contact forces during walking in adults.

Scientific reports·2026

Same author

Does osteogenesis imperfecta predispose infants to metaphyseal fractures? A systematic review.

BMJ paediatrics open·2026

Same author

Emulsion templating of PCL:PGS methacrylate blends for soft tissue engineering.

Frontiers in bioengineering and biotechnology·2026

Same author

Developing an artificial intelligence tool for detecting fractures of child abuse: preliminary findings.

European radiology·2026

Search research articles

Related Experiment Video

Updated: Apr 14, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

Developing CT based computational models of pediatric femurs.

Xinshan Li¹, Marco Viceconti¹, Marta C Cohen²

¹Department of Mechanical Engineering, University of Sheffield, Sheffield, UK; Insigneo Institute for in Silico Medicine, University of Sheffield, Sheffield, UK.

Journal of Biomechanics

|April 22, 2015

Summary

Understanding pediatric bone fractures is crucial. This study uses computational models to show rapid changes in infant femur geometry and mechanical properties shortly after birth.

Keywords:

Bone development Bone mechanical properties Finite element models Pediatric long bone

More Related Videos

A Method to Estimate Cadaveric Femur Cortical Strains During Fracture Testing Using Digital Image Correlation

A Method to Estimate Cadaveric Femur Cortical Strains During Fracture Testing Using Digital Image Correlation

Published on: September 14, 2017

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

Related Experiment Videos

Last Updated: Apr 14, 2026

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Subject-specific Musculoskeletal Model for Studying Bone Strain During Dynamic Motion

Published on: April 11, 2018

A Method to Estimate Cadaveric Femur Cortical Strains During Fracture Testing Using Digital Image Correlation

A Method to Estimate Cadaveric Femur Cortical Strains During Fracture Testing Using Digital Image Correlation

Published on: September 14, 2017

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Proximal Cadaveric Femur Preparation for Fracture Strength Testing and Quantitative CT-based Finite Element Analysis

Published on: March 11, 2017

Area of Science:

Biomechanics
Pediatric Orthopedics
Computational Modeling

Background:

Fracture mechanisms in young children remain poorly understood.
Limited research exists on pediatric bone mechanical properties under fracture loading.
Understanding these mechanisms aids in diagnosing injuries and bone fragility diseases.

Purpose of the Study:

To develop in silico (computational) femoral models from CT scans for infants and toddlers.
To provide quantitative data on pediatric femur geometry and mechanical response.
To investigate potential injury mechanisms and bone development.

Main Methods:

Utilized 15 anonymized QCT scans from children aged 0-3 years.
Created personalized computational models of femurs.
Performed four-point bending simulations on the models with varying loads.

Main Results:

Femoral mid-shaft cross-sections evolved from circular at birth to elliptical with age.
Bone density and elastic modulus increased and became more differentiated with growth.
Adult-like cortical bone density was achieved within weeks of birth.

Conclusions:

In silico models can capture quantitative variations in pediatric femur geometry, material properties, and mechanical responses.
These models confirm the rapid bone development in early childhood.
This approach has potential for investigating pediatric bone injury mechanisms.