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Predictors of Outcome of Convulsive Status Epilepticus Among an Egyptian Pediatric Tertiary Hospital

Eman F Halawa1, Iman Draz2, Dalia Ahmed2

  • 1Faculty of Medicine, Cairo University, Cairo, Egypt emanhalawa3@yahoo.com.

Journal of Child Neurology
|April 22, 2015
PubMed

Insights

Pediatric convulsive status epilepticus (CSE) is often caused by acute symptoms. Lower Glasgow Coma Scale scores and refractory CSE predict poor outcomes, including mortality and disability.

Area of Science:

  • Neurology
  • Pediatrics

Background:

  • Convulsive status epilepticus (CSE) is a frequent pediatric neurologic emergency.
  • Understanding its causes and predictors of outcome is crucial for effective management.

Purpose of the Study:

  • To investigate the etiology, clinical features, and prognostic factors of CSE in children.
  • To evaluate patient outcomes using the Glasgow Outcome Score.

Main Methods:

  • A cohort study involving seventy pediatric patients diagnosed with CSE.
  • Data collected from the pediatric emergency department of Cairo University Children's Hospital.
  • Outcome assessment utilized the Glasgow Outcome Score.

Main Results:

  • Acute symptomatic etiology was the most frequent cause of CSE.
  • Refractory CSE was more prevalent in acute symptomatic cases.
  • Outcomes included mortality (37.1%), severe disability (21.4%), moderate disability (24.3%), and good recovery (17.1%).

Conclusions:

  • Lower admission modified Glasgow Coma Scale scores significantly predicted mortality.
  • Both lower admission modified Glasgow Coma Scale scores and refractory CSE were significant predictors of disability and mortality.

Keywords:
convulsive status epilepticusoutcomepredictors

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